296997

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 1031789..1032297 Replicon chromosome
Accession NZ_OX460910
Organism Photobacterium phosphoreum strain MIP2473 isolate MIP2473

Toxin (Protein)


Gene name relB Uniprot ID A0A2T3PYA4
Locus tag QOS47_RS19335 Protein ID WP_045032845.1
Coordinates 1031789..1032049 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A2T3PSM4
Locus tag QOS47_RS19340 Protein ID WP_045032846.1
Coordinates 1032046..1032297 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QOS47_RS19310 1027196..1027576 + 381 WP_107293623.1 hypothetical protein -
QOS47_RS19315 1027610..1028026 - 417 WP_065193249.1 GFA family protein -
QOS47_RS19320 1028167..1029039 - 873 WP_065207857.1 class I SAM-dependent methyltransferase -
QOS47_RS19325 1029299..1029589 - 291 WP_045032289.1 hypothetical protein -
QOS47_RS19330 1029946..1030827 - 882 WP_283598836.1 NAD(P)-dependent oxidoreductase -
QOS47_RS19335 1031789..1032049 - 261 WP_045032845.1 Txe/YoeB family addiction module toxin Toxin
QOS47_RS19340 1032046..1032297 - 252 WP_045032846.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QOS47_RS19345 1033136..1033660 - 525 WP_045032847.1 DUF2442 domain-containing protein -
QOS47_RS19350 1033654..1033925 - 272 Protein_848 DUF4160 domain-containing protein -
QOS47_RS19355 1034512..1035036 + 525 WP_283599192.1 tyrosine-type recombinase/integrase -
QOS47_RS19360 1035033..1036091 + 1059 WP_283598840.1 IS91 family transposase -
QOS47_RS19365 1036312..1036950 - 639 WP_283598843.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10279.70 Da        Isoelectric Point: 8.8610

>T296997 WP_045032845.1 NZ_OX460910:c1032049-1031789 [Photobacterium phosphoreum]
MSRMLAWTDDAWDDYLYWQGQDKKTLKRINKLITDTKRSPFEGIGKPEPLKENLAGFWSRRIDDTNRLVYVVNDAHLTII
SCRYHY

Download         Length: 261 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9261.37 Da        Isoelectric Point: 4.4865

>AT296997 WP_045032846.1 NZ_OX460910:c1032297-1032046 [Photobacterium phosphoreum]
MRIVSFTEARNGLKSVLDGVVNDADCTIITRRDSEDAVVMSMDYYNSLMETIYLSRSPANAAHLNKSIAQYNAGQTTERD
LLE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2T3PYA4

Antitoxin

Source ID Structure
AlphaFold DB A0A2T3PSM4

References