296995

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1817537..1818059 Replicon chromosome
Accession NZ_OX460909
Organism Photobacterium phosphoreum strain MIP2473 isolate MIP2473

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QOS47_RS08580 Protein ID WP_232611433.1
Coordinates 1817775..1818059 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID B5EU68
Locus tag QOS47_RS08575 Protein ID WP_012535627.1
Coordinates 1817537..1817785 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QOS47_RS08535 1812618..1812887 + 270 Protein_1574 phage integrase N-terminal SAM-like domain-containing protein -
QOS47_RS08540 1812971..1813243 + 273 WP_065209072.1 DUF1778 domain-containing protein -
QOS47_RS08545 1813240..1813746 + 507 WP_279143375.1 GNAT family N-acetyltransferase -
QOS47_RS08550 1813925..1814200 + 276 Protein_1577 site-specific integrase -
QOS47_RS08555 1814793..1815878 + 1086 WP_283597469.1 hypothetical protein -
QOS47_RS08560 1816075..1816347 + 273 Protein_1579 site-specific integrase -
QOS47_RS08565 1816801..1817046 - 246 WP_105063926.1 CopG family transcriptional regulator -
QOS47_RS08570 1817090..1817299 - 210 WP_107293800.1 BrnT family toxin -
QOS47_RS08575 1817537..1817785 + 249 WP_012535627.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QOS47_RS08580 1817775..1818059 + 285 WP_232611433.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QOS47_RS08585 1818210..1818527 + 318 WP_283598093.1 phage integrase N-terminal SAM-like domain-containing protein -
QOS47_RS08590 1818485..1818787 + 303 Protein_1585 transposase -
QOS47_RS08595 1819016..1819468 - 453 WP_283597470.1 hypothetical protein -
QOS47_RS08600 1819731..1820621 + 891 Protein_1587 site-specific integrase -
QOS47_RS08605 1820618..1821676 + 1059 WP_283597471.1 IS91 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1810010..1824163 14153
- inside IScluster/Tn - - 1813922..1820621 6699


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(12-73)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11014.93 Da        Isoelectric Point: 10.4661

>T296995 WP_232611433.1 NZ_OX460909:1817775-1818059 [Photobacterium phosphoreum]
MTYKLDFKKSAYKEWNKLGATLREQFKKKLLERLDNPHVPASKLSGADNLYKIKLQQSGYRLVYKVEDDVIIVTVLAVGK
RERSDVYKKAMHRI

Download         Length: 285 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9060.25 Da        Isoelectric Point: 3.9607

>AT296995 WP_012535627.1 NZ_OX460909:1817537-1817785 [Photobacterium phosphoreum]
MTTRILADVAASITEFKANPMKVASSAYGEAVAVLNRNEPAFYCVPAEAYELLMDRIEDLELLSLAAERENEETISVDIH
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB B5EU68

References