Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapB(antitoxin)
Location 74523..75097 Replicon plasmid p81
Accession NZ_OX458337
Organism Pseudomonas syringae pv. tomato strain DAPP-PG 215 isolate IPVPG 215

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QWJ11_RS29460 Protein ID WP_007247235.1
Coordinates 74523..74900 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID Q48BC4
Locus tag QWJ11_RS29465 Protein ID WP_004644067.1
Coordinates 74897..75097 (-) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QWJ11_RS29440 (DAPPPG215_29780) 69770..70372 + 603 WP_007247239.1 conjugal transfer protein TraX -
QWJ11_RS29445 (DAPPPG215_29785) 70401..72542 + 2142 WP_007247238.1 DotA/TraY family protein -
QWJ11_RS29450 (DAPPPG215_29790) 72591..73238 + 648 WP_007247237.1 plasmid IncI1-type surface exclusion protein ExcA -
QWJ11_RS29455 (DAPPPG215_29795) 73331..74533 + 1203 WP_007247236.1 hypothetical protein -
QWJ11_RS29460 (DAPPPG215_29800) 74523..74900 - 378 WP_007247235.1 PIN domain-containing protein Toxin
QWJ11_RS29465 (DAPPPG215_29805) 74897..75097 - 201 WP_004644067.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QWJ11_RS29470 (DAPPPG215_29810) 75190..76275 + 1086 WP_007247234.1 thioredoxin fold domain-containing protein -
QWJ11_RS29475 (DAPPPG215_29815) 76262..78550 + 2289 WP_007247233.1 F-type conjugative transfer protein TrbC -
QWJ11_RS29480 (DAPPPG215_29820) 78683..79000 + 318 WP_223285740.1 hypothetical protein -
QWJ11_RS29485 (DAPPPG215_29825) 79021..79584 + 564 WP_010214078.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..80904 80904


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-113)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 13623.69 Da        Isoelectric Point: 6.4723

>T296988 WP_007247235.1 NZ_OX458337:c74900-74523 [Pseudomonas syringae pv. tomato]
VKGVLVDTSVWVEHFRNNSPELVNLLSQDRVLIHPMVIGELACGTPPDRSNTLTDLGDLRGAQQPTVSEVIAFLNTHKLY
GLGCGLVDMTLLASALLSGTALWTLDKRLERLASRMAVSYQPSTH

Download         Length: 378 bp

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7445.66 Da        Isoelectric Point: 7.0102

>AT296988 WP_004644067.1 NZ_OX458337:c75097-74897 [Pseudomonas syringae pv. tomato]
MRTTVTIDDALYQRALEVADPAMDKADLFREAVQTFVRIQAAKRLMALGATLPTMEDIARRHEKAL

Download         Length: 201 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2S4IKB9

References