Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2157672..2158185 Replicon chromosome
Accession NZ_OX458335
Organism Pseudomonas syringae pv. tomato strain DAPP-PG 215 isolate IPVPG 215

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QWJ11_RS10260 Protein ID WP_007245247.1
Coordinates 2157672..2157956 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S6UR83
Locus tag QWJ11_RS10265 Protein ID WP_005740683.1
Coordinates 2157946..2158185 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QWJ11_RS10240 (DAPPPG215_10330) 2153081..2153566 + 486 WP_007245243.1 DUF2269 domain-containing protein -
QWJ11_RS10245 (DAPPPG215_10335) 2153818..2155746 + 1929 WP_007245244.1 methyl-accepting chemotaxis protein -
QWJ11_RS10250 (DAPPPG215_10340) 2155775..2156707 - 933 WP_007245245.1 DMT family transporter -
QWJ11_RS10255 (DAPPPG215_10345) 2156782..2157636 + 855 WP_007245246.1 LysR family transcriptional regulator -
QWJ11_RS10260 2157672..2157956 - 285 WP_007245247.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QWJ11_RS10265 (DAPPPG215_10350) 2157946..2158185 - 240 WP_005740683.1 ribbon-helix-helix protein, CopG family Antitoxin
QWJ11_RS10270 (DAPPPG215_10355) 2158354..2159370 - 1017 WP_003376162.1 1-aminocyclopropane-1-carboxylate deaminase -
QWJ11_RS10275 (DAPPPG215_10360) 2159536..2160042 + 507 WP_007245249.1 winged helix-turn-helix transcriptional regulator -
QWJ11_RS10280 (DAPPPG215_10365) 2160190..2161098 + 909 WP_010203521.1 DUF808 domain-containing protein -
QWJ11_RS10285 (DAPPPG215_10370) 2161225..2162010 - 786 WP_007245250.1 outer membrane protein OmpK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-40)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10828.58 Da        Isoelectric Point: 10.0884

>T296984 WP_007245247.1 NZ_OX458335:c2157956-2157672 [Pseudomonas syringae pv. tomato]
MQVEWLKTALKNLDDEAAYISLENPAAAVAFVEAIQISVKQLASFPALGREGRIAGTREWPLPDWPYLIPYRIRNGRLQV
LRIFHTRRQSPLVW

Download         Length: 285 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8753.90 Da        Isoelectric Point: 4.5822

>AT296984 WP_005740683.1 NZ_OX458335:c2158185-2157946 [Pseudomonas syringae pv. tomato]
MSVMSLRLPDEMADTLAHLAKATGRSKSFLALNALREYLTREAWQIAEIQRAIEEADAGEFASEEDVKAVMNKWANNAG

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8M7Q4

References