296983

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1096283..1096917 Replicon chromosome
Accession NZ_OX458335
Organism Pseudomonas syringae pv. tomato strain DAPP-PG 215 isolate IPVPG 215

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QWJ11_RS05290 Protein ID WP_003380365.1
Coordinates 1096283..1096687 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID Q888H8
Locus tag QWJ11_RS05295 Protein ID WP_003380366.1
Coordinates 1096687..1096917 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QWJ11_RS05260 (DAPPPG215_05290) 1092169..1092651 + 483 WP_002556144.1 PAS domain-containing protein -
QWJ11_RS05265 (DAPPPG215_05295) 1092747..1094003 + 1257 WP_007244165.1 3-phosphoshikimate 1-carboxyvinyltransferase -
QWJ11_RS05270 (DAPPPG215_05300) 1094025..1094687 - 663 WP_005770944.1 ChrR family anti-sigma-E factor -
QWJ11_RS05275 (DAPPPG215_05305) 1094687..1095199 - 513 WP_005615033.1 sigma-70 family RNA polymerase sigma factor -
QWJ11_RS05280 (DAPPPG215_05310) 1095260..1096099 + 840 WP_225982956.1 hypothetical protein -
QWJ11_RS05285 1096132..1096251 - 120 Protein_1030 aldose 1-epimerase -
QWJ11_RS05290 (DAPPPG215_05315) 1096283..1096687 - 405 WP_003380365.1 tRNA(fMet)-specific endonuclease VapC Toxin
QWJ11_RS05295 (DAPPPG215_05320) 1096687..1096917 - 231 WP_003380366.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QWJ11_RS05300 (DAPPPG215_05325) 1097031..1097912 - 882 WP_007244162.1 aldose 1-epimerase -
QWJ11_RS05305 (DAPPPG215_05330) 1097887..1098858 - 972 WP_007244161.1 DMT family transporter -
QWJ11_RS05310 (DAPPPG215_05335) 1098942..1100222 - 1281 WP_005736622.1 TRAP transporter large permease -
QWJ11_RS05315 (DAPPPG215_05340) 1100223..1100750 - 528 WP_005770954.1 TRAP transporter small permease -
QWJ11_RS05320 (DAPPPG215_05345) 1100814..1101839 - 1026 WP_005770956.1 TRAP transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-34)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14814.09 Da        Isoelectric Point: 6.8615

>T296983 WP_003380365.1 NZ_OX458335:c1096687-1096283 [Pseudomonas syringae pv. tomato]
MLKYMLDTNICIFTIKNKPVSVREAFNLHHGQLCISAITLMELVYGAEKSSSPERNLAVVEGFAARLELLPYDSAAAAHT
GMIRAELARAGTPIGPYDQMIAGHARSLGLVVITNNQREFQRVEGLRVEDWVSQ

Download         Length: 405 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8593.67 Da        Isoelectric Point: 4.5557

>AT296983 WP_003380366.1 NZ_OX458335:c1096917-1096687 [Pseudomonas syringae pv. tomato]
MEQSTVFKSNRSQAVRLPKAVALPDDVKRVDVVAVGRTRIISPAGEMWNSWFDGESVSDDFMAEREQPVEQLRESL

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8LU44

References