Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1493919..1495441 Replicon chromosome
Accession NZ_OX458332
Organism Methylococcus capsulatus isolate Mc(Nor)

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag QMX71_RS07035 Protein ID WP_282213665.1
Coordinates 1494515..1495441 (+) Length 309 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag QMX71_RS07030 Protein ID WP_026045817.1
Coordinates 1493919..1494518 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMX71_RS07005 (MCNOR_1477) 1489732..1490637 + 906 WP_017364399.1 methylenetetrahydromethanopterin dehydrogenase -
QMX71_RS07010 (MCNOR_1478) 1490707..1491192 - 486 WP_017364398.1 hypothetical protein -
QMX71_RS07015 (MCNOR_1479) 1491199..1491621 - 423 WP_017364397.1 YeeE/YedE thiosulfate transporter family protein -
QMX71_RS07020 (MCNOR_1480) 1491817..1493007 + 1191 WP_282213664.1 PQQ-dependent sugar dehydrogenase -
QMX71_RS07030 (MCNOR_1482) 1493919..1494518 + 600 WP_026045817.1 AbiEi antitoxin N-terminal domain-containing protein Antitoxin
QMX71_RS07035 (MCNOR_1483) 1494515..1495441 + 927 WP_282213665.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
QMX71_RS07040 (MCNOR_1484) 1495438..1495926 + 489 WP_282213666.1 hypothetical protein -
QMX71_RS07045 (MCNOR_1485) 1495923..1496510 + 588 WP_282213667.1 hypothetical protein -
QMX71_RS07050 (MCNOR_1486) 1496543..1497046 - 504 WP_282213668.1 hypothetical protein -
QMX71_RS07055 (MCNOR_1487) 1497043..1497723 - 681 WP_282213669.1 recombinase family protein -
QMX71_RS07060 (MCNOR_1488) 1497733..1497861 - 129 WP_248617047.1 recombinase family protein -
QMX71_RS07065 (MCNOR_1489) 1497834..1498400 - 567 WP_282213670.1 recombinase family protein -
QMX71_RS07070 (MCNOR_1490) 1498397..1498894 - 498 WP_282213671.1 DUF2924 domain-containing protein -
QMX71_RS07075 1498924..1499091 + 168 WP_282213177.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(36-257)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(8-53)


Sequences

Toxin        


Download         Length: 309 a.a.        Molecular weight: 34397.16 Da        Isoelectric Point: 6.1649

>T296978 WP_282213665.1 NZ_OX458332:1494515-1495441 [Methylococcus capsulatus]
VSSRNTAASVRARLLAKARTDKQDFNLVLTRYALERLLYRLSVSAHADHFLLKGALLFDLWFDIPHRPTRDADLLGFGSA
EIPHVEAAFRDICAVELDDGIRFQADSVHAEEIRKEANYSGVRVTLIGLLDGARCHVQVDVGFGDAVTPGPETVDYPVML
SEMPAPKLRAYPRYTVIAEKLEALVSLGIANSRMKDYFDLWILSRYTDFDGKLLCNAIHATFERRRTPLPDGVPFGLSDE
FAQDRQKQTQWQAFLRKNALVELALSEVVAGLRAFLSVPLDALQQGAAFPQTWLAGNGWTSSSEEFSR

Download         Length: 927 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22277.00 Da        Isoelectric Point: 10.2215

>AT296978 WP_026045817.1 NZ_OX458332:1493919-1494518 [Methylococcus capsulatus]
MDSSHQSILDLAAQRGLIRPRDLNERGLPTVALTRLVRQGLLQRVGRGLYAIPDRAVSEHGALAEVARKHPQAIVCLLSA
LRLHELTTQSPFEVWLAIPNKARAPKMDYPPLRIVRFSGAALTEGVEEHLIDGVPVRVTNVARTVADCFKYRNKIGLDVA
LEALREAWKAKRVGMDELWQFAKLCRVANVMRPYLESLT

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References