Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 3432505..3433021 Replicon chromosome
Accession NZ_OX442412
Organism Salmonella enterica subsp. enterica serovar Rissen isolate pure strain

Toxin (Protein)


Gene name relE Uniprot ID C0Q7A9
Locus tag QM550_RS16905 Protein ID WP_000220578.1
Coordinates 3432737..3433021 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID V7ISI8
Locus tag QM550_RS16900 Protein ID WP_000212724.1
Coordinates 3432505..3432747 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QM550_RS16880 (3427525) 3427525..3428658 + 1134 WP_023138829.1 amidohydrolase/deacetylase family metallohydrolase -
QM550_RS16885 (3428642) 3428642..3429760 + 1119 WP_023138828.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -
QM550_RS16890 (3429757) 3429757..3430497 + 741 WP_023138827.1 KDGP aldolase family protein -
QM550_RS16895 (3430514) 3430514..3432427 + 1914 WP_023203318.1 BglG family transcription antiterminator -
QM550_RS16900 (3432505) 3432505..3432747 + 243 WP_000212724.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
QM550_RS16905 (3432737) 3432737..3433021 + 285 WP_000220578.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QM550_RS16910 (3433025) 3433025..3433489 - 465 WP_017441190.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
QM550_RS16915 (3433706) 3433706..3435844 - 2139 WP_000187818.1 anaerobic ribonucleoside-triphosphate reductase -
QM550_RS16920 (3436253) 3436253..3437905 - 1653 WP_023138463.1 alpha,alpha-phosphotrehalase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-80)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10854.67 Da        Isoelectric Point: 10.0482

>T296967 WP_000220578.1 NZ_OX442412:3432737-3433021 [Salmonella enterica subsp. enterica serovar Rissen]
MTYELEFDPRALKEWHKLGDTVKAQLKKKLADVLLNPRIDSARLNGLPDCYKIKLKSSGYRLVYQVRDDVVIVFVVAVGK
REHSAVYHDANKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8961.34 Da        Isoelectric Point: 5.0651

>AT296967 WP_000212724.1 NZ_OX442412:3432505-3432747 [Salmonella enterica subsp. enterica serovar Rissen]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTLSDSEDALIQTVRERLSSPQKGIKVSLDDL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E876

Antitoxin

Source ID Structure
AlphaFold DB A0A5H5JRI5

References