296957

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-YafN
Location 651245..651767 Replicon chromosome
Accession NZ_OX442412
Organism Salmonella enterica subsp. enterica serovar Rissen isolate pure strain

Toxin (Protein)


Gene name stbE Uniprot ID V7IL40
Locus tag QM550_RS03360 Protein ID WP_000221345.1
Coordinates 651245..651529 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID V1H457
Locus tag QM550_RS03365 Protein ID WP_000885424.1
Coordinates 651519..651767 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QM550_RS03340 (647320) 647320..648828 - 1509 WP_023138146.1 FAD-dependent oxidoreductase -
QM550_RS03345 (648873) 648873..649361 + 489 WP_023138147.1 MarR family winged helix-turn-helix transcriptional regulator -
QM550_RS03350 (649554) 649554..650627 + 1074 WP_023138148.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
QM550_RS03355 (650685) 650685..651074 - 390 WP_000194089.1 RidA family protein -
QM550_RS03360 (651245) 651245..651529 - 285 WP_000221345.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QM550_RS03365 (651519) 651519..651767 - 249 WP_000885424.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QM550_RS03370 (652180) 652180..652533 - 354 WP_000418733.1 hypothetical protein -
QM550_RS03375 (652536) 652536..652925 - 390 WP_001044696.1 hypothetical protein -
QM550_RS03380 (653290) 653290..653397 + 108 Protein_664 IS110 family transposase -
QM550_RS03385 (653804) 653804..654136 + 333 WP_023138149.1 DUF1493 family protein -
QM550_RS03390 (654411) 654411..654599 - 189 WP_001276021.1 DUF29 family protein -
QM550_RS03395 (655012) 655012..655920 + 909 WP_023138150.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 648873..658792 9919


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11043.79 Da        Isoelectric Point: 10.6500

>T296957 WP_000221345.1 NZ_OX442412:c651529-651245 [Salmonella enterica subsp. enterica serovar Rissen]
MTYKLAFNESALKEWKKLGHTIQEQFKKKLRERLENPRVPASQLHGRKDQYKIKLRGAGYRLVYSVEDEIITVTVIGVGK
RENDAVYKVTRHRS

Download         Length: 285 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9090.32 Da        Isoelectric Point: 3.9820

>AT296957 WP_000885424.1 NZ_OX442412:c651767-651519 [Salmonella enterica subsp. enterica serovar Rissen]
MAFQILTTTAASITELKRDPMGTFNAGDGAPVAILNRNEPAFYCVPPALYAHLMDILEDEELGRIIDERANERVIEVNID
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5Y2FFA8

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0WPN5

References