Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 3649826..3650383 Replicon chromosome
Accession NZ_OX419519
Organism Kitasatospora sp. DSM 114396 isolate DSM_114396

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QMQ26_RS16860 Protein ID WP_282206222.1
Coordinates 3649826..3650107 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QMQ26_RS16865 Protein ID WP_282206542.1
Coordinates 3650114..3650383 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMQ26_RS16850 3646493..3648946 + 2454 WP_282206220.1 helicase C-terminal domain-containing protein -
QMQ26_RS16855 3649201..3649608 + 408 WP_282206221.1 carboxymuconolactone decarboxylase family protein -
QMQ26_RS16860 3649826..3650107 - 282 WP_282206222.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QMQ26_RS16865 3650114..3650383 - 270 WP_282206542.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QMQ26_RS16870 3650474..3651148 - 675 WP_282206223.1 hypothetical protein -
QMQ26_RS16875 3651257..3651892 + 636 WP_282206224.1 TetR/AcrR family transcriptional regulator -
QMQ26_RS16880 3652213..3652434 - 222 WP_100837429.1 hypothetical protein -
QMQ26_RS16885 3652884..3653087 + 204 WP_030918248.1 cold-shock protein -
QMQ26_RS16890 3653403..3654812 + 1410 WP_282206225.1 DEAD/DEAH box helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(4-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10743.42 Da        Isoelectric Point: 11.5385

>T296751 WP_282206222.1 NZ_OX419519:c3650107-3649826 [Kitasatospora sp. DSM 114396]
MGHVTRFTPRAQRDLLKIERSDALRILRRLADLQRAMDLGDTTAFDVKALQGHAARWRLRIGDHRAVYTVENGQLIIWVL
GVGHRSDIYRQLP

Download         Length: 282 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10094.30 Da        Isoelectric Point: 4.4247

>AT296751 WP_282206542.1 NZ_OX419519:c3650383-3650114 [Kitasatospora sp. DSM 114396]
MIESMAEVRSHLADVIDRARREETPTIITRRGKQEAVVIDIEEYRRLRRIADAAEDAWLNRLADESEAEGLQGSVSLEEM
AALLRSQEG

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References