Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 3639279..3639820 Replicon chromosome
Accession NZ_OX419519
Organism Kitasatospora sp. DSM 114396 isolate DSM_114396

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QMQ26_RS16825 Protein ID WP_282206217.1
Coordinates 3639554..3639820 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QMQ26_RS16820 Protein ID WP_199847013.1
Coordinates 3639279..3639557 (+) Length 93 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMQ26_RS16790 3634607..3635206 - 600 WP_100838613.1 recombination mediator RecR -
QMQ26_RS16795 3635489..3635827 - 339 WP_100837462.1 YbaB/EbfC family nucleoid-associated protein -
QMQ26_RS16800 3636000..3638207 - 2208 WP_282206215.1 DNA polymerase III subunit gamma and tau -
QMQ26_RS16815 3638682..3639245 + 564 WP_282206216.1 SMI1/KNR4 family protein -
QMQ26_RS16820 3639279..3639557 + 279 WP_199847013.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QMQ26_RS16825 3639554..3639820 + 267 WP_282206217.1 Txe/YoeB family addiction module toxin Toxin
QMQ26_RS16830 3640074..3642161 + 2088 WP_282206218.1 histidine kinase -
QMQ26_RS16835 3642183..3642791 - 609 WP_100837437.1 response regulator transcription factor -
QMQ26_RS16840 3642877..3643611 + 735 WP_282206219.1 ABC transporter ATP-binding protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-86)

Antitoxin

(1-73)


Sequences


Toxin        


Download         Length: 89 a.a.        Molecular weight: 10475.91 Da        Isoelectric Point: 8.4927

>T296750 WP_282206217.1 NZ_OX419519:3639554-3639820 [Kitasatospora sp. DSM 114396]
VKIRFTDGGWADYLYWQANDRRLLKRINQLIEDIRRNGHEGIGKPEPLRHELAGAWSRRIDQEHRLVYVLDEPADTVCII
ACRYHYSK

Download         Length: 267 bp


Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10318.42 Da        Isoelectric Point: 4.1851

>AT296750 WP_199847013.1 NZ_OX419519:3639279-3639557 [Kitasatospora sp. DSM 114396]
MKTMSATELRSNLAAALDSVEDDAEELIITRAGHEPLVVVSLAEYASLRETDYLLRSPANAEHLRQSLRDYQEGRMQSRE
LIDPEDVTEQSA

Download         Length: 279 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References