Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | sanaTA/AbiEii-DUF6088 |
| Location | 59920..61279 | Replicon | plasmid p1 |
| Accession | NZ_OX411214 | ||
| Organism | Vibrio campbellii isolate BF5_0283 | ||
Toxin (Protein)
| Gene name | sanaT | Uniprot ID | - |
| Locus tag | QMX76_RS27835 | Protein ID | WP_282253014.1 |
| Coordinates | 59920..60873 (-) | Length | 318 a.a. |
Antitoxin (Protein)
| Gene name | sanaA | Uniprot ID | A0A2N7PH06 |
| Locus tag | QMX76_RS27840 | Protein ID | WP_008218079.1 |
| Coordinates | 60875..61279 (-) | Length | 135 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QMX76_RS27820 | 56376..57068 | - | 693 | WP_282253008.1 | hypothetical protein | - |
| QMX76_RS27825 | 57147..58379 | - | 1233 | WP_282253010.1 | restriction endonuclease subunit S | - |
| QMX76_RS27830 | 58369..59901 | - | 1533 | WP_282253012.1 | type I restriction-modification system subunit M | - |
| QMX76_RS27835 | 59920..60873 | - | 954 | WP_282253014.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| QMX76_RS27840 | 60875..61279 | - | 405 | WP_008218079.1 | DUF6088 family protein | Antitoxin |
| QMX76_RS27845 | 61467..61961 | - | 495 | WP_282253024.1 | tyrosine-type recombinase/integrase | - |
| QMX76_RS27850 | 62108..62458 | + | 351 | WP_282248671.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| QMX76_RS27855 | 62455..62811 | + | 357 | WP_105069498.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| QMX76_RS27860 | 62862..64460 | + | 1599 | WP_282248670.1 | IS66 family transposase | - |
| QMX76_RS27865 | 64909..65163 | + | 255 | WP_282253026.1 | YqaE/Pmp3 family membrane protein | - |
| QMX76_RS27870 | 65219..65794 | + | 576 | WP_282253028.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..150483 | 150483 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 318 a.a. Molecular weight: 36706.38 Da Isoelectric Point: 5.5213
>T296749 WP_282253014.1 NZ_OX411214:c60873-59920 [Vibrio campbellii]
MEKLKQQFLEVSDALELGNPAIIEKDYWVVALLSELAKVSPVNHQMVFSGGTALAKSNVKILRMSEDVDIKLIPHQEFGE
LSRGQKKAARKTCINEIEMAITQTERFTVESRLVRDEYRYVEFELRYPQQFSQAPCLRPIIKLELIETIPLLDLEPRPIQ
SLVAELYRQPQEVKAFDCVSIQATLVEKVISMLRRTMSVKRDTQRKDDATLVRHIYDVYCILKTEAQLENFDLTAMTALF
NTVLKEDIDRFGNQHTEFVANPKQELQLGLKELEDNPVFRQRFQDFVTPMVFNTEPHDFDTCFASFKRVAQSLIKTI
MEKLKQQFLEVSDALELGNPAIIEKDYWVVALLSELAKVSPVNHQMVFSGGTALAKSNVKILRMSEDVDIKLIPHQEFGE
LSRGQKKAARKTCINEIEMAITQTERFTVESRLVRDEYRYVEFELRYPQQFSQAPCLRPIIKLELIETIPLLDLEPRPIQ
SLVAELYRQPQEVKAFDCVSIQATLVEKVISMLRRTMSVKRDTQRKDDATLVRHIYDVYCILKTEAQLENFDLTAMTALF
NTVLKEDIDRFGNQHTEFVANPKQELQLGLKELEDNPVFRQRFQDFVTPMVFNTEPHDFDTCFASFKRVAQSLIKTI
Download Length: 954 bp
Antitoxin
Download Length: 135 a.a. Molecular weight: 15322.71 Da Isoelectric Point: 10.8824
>AT296749 WP_008218079.1 NZ_OX411214:c61279-60875 [Vibrio campbellii]
MTAVERVYQKIKRSRRYVFERKDFDGFASYDQIGRALRQLVKQGELIKLGYGLYTKARMNSLTGRPMPTNPGGSDALMRE
ILKMKGVDFEMDKLSLQSLSGKSTQIPSSIQYSWNHKQFNRKLAVGNRVLNSPS
MTAVERVYQKIKRSRRYVFERKDFDGFASYDQIGRALRQLVKQGELIKLGYGLYTKARMNSLTGRPMPTNPGGSDALMRE
ILKMKGVDFEMDKLSLQSLSGKSTQIPSSIQYSWNHKQFNRKLAVGNRVLNSPS
Download Length: 405 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|