Detailed information of TA system TA296745

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 1535575..1536103
• Replicon: chromosome
• Accession: NZ_OX411212
• Organism: Vibrio campbellii isolate BF5_0283

Toxin (Protein)

• Gene name: relE
• Uniprot ID: K5TRR0
• Locus tag: QMX76_RS07540
• Protein ID: WP_005377002.1
• Coordinates: 1535575..1535865 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: QMX76_RS07545
• Protein ID: WP_229631645.1
• Coordinates: 1535855..1536103 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QMX76_RS07475	1530726..1530818	+	93	WP_193238457.1	DUF3265 domain-containing protein	-
QMX76_RS07480	1531220..1531342	+	123	WP_282250222.1	DUF3265 domain-containing protein	-
QMX76_RS07485	1531371..1532030	+	660	WP_282249026.1	hypothetical protein	-
QMX76_RS07490	1532045..1532137	+	93	WP_282249027.1	DUF3265 domain-containing protein	-
QMX76_RS07495	1532236..1532667	+	432	WP_045392990.1	GNAT family N-acetyltransferase	-
QMX76_RS07500	1532963..1533661	+	699	WP_072606224.1	hypothetical protein	-
QMX76_RS07505	1533685..1533777	+	93	WP_005377014.1	DUF3265 domain-containing protein	-
QMX76_RS07510	1533808..1534329	+	522	WP_282249028.1	GNAT family N-acetyltransferase	-
QMX76_RS07515	1534360..1534452	+	93	WP_080540751.1	DUF3265 domain-containing protein	-
QMX76_RS07520	1534500..1534868	+	369	WP_069549244.1	hypothetical protein	-
QMX76_RS07525	1534859..1534921	+	63	Protein_1403	DUF3265 domain-containing protein	-
QMX76_RS07530	1535003..1535449	+	447	WP_282249029.1	hypothetical protein	-
QMX76_RS07535	1535464..1535556	+	93	WP_079854231.1	DUF3265 domain-containing protein	-
QMX76_RS07540	1535575..1535865	-	291	WP_005377002.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
QMX76_RS07545	1535855..1536103	-	249	WP_229631645.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
QMX76_RS07550	1536178..1536246	+	69	WP_074531725.1	DUF3265 domain-containing protein	-
QMX76_RS07555	1536300..1536533	+	234	WP_005377029.1	hypothetical protein	-
QMX76_RS07560	1536603..1536692	+	90	WP_193222964.1	DUF3265 domain-containing protein	-
QMX76_RS07565	1536726..1537907	+	1182	WP_282249030.1	hypothetical protein	-
QMX76_RS07570	1537922..1538014	+	93	WP_080256992.1	DUF3265 domain-containing protein	-
QMX76_RS07575	1538040..1539065	+	1026	WP_134837661.1	LD-carboxypeptidase	-
QMX76_RS07580	1539191..1539874	+	684	WP_282249031.1	hypothetical protein	-
QMX76_RS07585	1539871..1540095	+	225	WP_282249032.1	hypothetical protein	-
QMX76_RS07590	1540110..1540202	+	93	WP_004402681.1	DUF3265 domain-containing protein	-
QMX76_RS07595	1540231..1540917	+	687	WP_110416610.1	DUF4336 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1456846..1591556	134710
	-	inside	Integron	-	-	1455649..1585468	129819

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-83)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (12-75)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 11261.25 Da
• Isoelectric Point: 10.5932

>T296745 WP_005377002.1 NZ_OX411212:c1535865-1535575 [Vibrio campbellii]
MTYKLDFKKSALKEWKKLGSTLQQQFKKKLIERLDNPHVPASKLSGADNMYKIKLRQSGYRLVYKVEDDVIIVTVLAVGK
RERSDVYRKAMKRLDD

Nucleotide

• Length: 291 bp

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9049.34 Da
• Isoelectric Point: 3.9610

>AT296745 WP_229631645.1 NZ_OX411212:c1536103-1535855 [Vibrio campbellii]
MATRILADVAASITELKANPMKVATSAYGEPVAVLNRNEPAFYCVPAEAYEMMMDRLEDLELLAIAKERESEESISVNID
DL

Nucleotide

• Length: 249 bp

Structures

Toxin

• AlphaFold DB: A0A347UR03