Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1482563..1483091 Replicon chromosome
Accession NZ_OX411212
Organism Vibrio campbellii isolate BF5_0283

Toxin (Protein)


Gene name relE Uniprot ID F7YRA6
Locus tag QMX76_RS06925 Protein ID WP_013868556.1
Coordinates 1482804..1483091 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A4Y8W958
Locus tag QMX76_RS06920 Protein ID WP_017038856.1
Coordinates 1482563..1482814 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMX76_RS06875 1478014..1478373 - 360 WP_282250321.1 hypothetical protein -
QMX76_RS06880 1478502..1478591 + 90 WP_072606010.1 DUF3265 domain-containing protein -
QMX76_RS06885 1478712..1478993 - 282 WP_282248986.1 hypothetical protein -
QMX76_RS06890 1479308..1479613 - 306 WP_282248987.1 hypothetical protein -
QMX76_RS06895 1479700..1479831 + 132 WP_079402534.1 DUF3265 domain-containing protein -
QMX76_RS06900 1479864..1480223 - 360 WP_282250324.1 hypothetical protein -
QMX76_RS06905 1480352..1480441 + 90 WP_072606010.1 DUF3265 domain-containing protein -
QMX76_RS06910 1480490..1481230 + 741 WP_282248988.1 abortive infection system antitoxin AbiGi family protein -
QMX76_RS06915 1481251..1481343 + 93 WP_282250189.1 DUF3265 domain-containing protein -
QMX76_RS06920 1482563..1482814 + 252 WP_017038856.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QMX76_RS06925 1482804..1483091 + 288 WP_013868556.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QMX76_RS06930 1483792..1484217 + 426 WP_140284315.1 hypothetical protein -
QMX76_RS06935 1484379..1485116 + 738 WP_282248989.1 SDR family oxidoreductase -
QMX76_RS06940 1485722..1485853 + 132 WP_159657865.1 DUF3265 domain-containing protein -
QMX76_RS06945 1486299..1486388 + 90 WP_072609598.1 DUF3265 domain-containing protein -
QMX76_RS06950 1486459..1486608 - 150 WP_086459347.1 hypothetical protein -
QMX76_RS06955 1486754..1486846 + 93 WP_079856562.1 DUF3265 domain-containing protein -
QMX76_RS06960 1486896..1487366 + 471 WP_282248990.1 GNAT family N-acetyltransferase -
QMX76_RS06965 1487396..1487488 + 93 WP_196333609.1 DUF3265 domain-containing protein -
QMX76_RS06970 1487579..1487857 + 279 WP_282248991.1 hypothetical protein -
QMX76_RS06975 1487875..1487964 + 90 WP_072829115.1 DUF3265 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1456846..1591556 134710
- inside Integron - - 1455649..1585468 129819


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(11-70)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11064.07 Da        Isoelectric Point: 10.5506

>T296744 WP_013868556.1 NZ_OX411212:1482804-1483091 [Vibrio campbellii]
MTYKLKFLPAAKKEWSKLAPPIQSQFKKKLKERLENPHVPSSKLRGYDSVYKIKLRTAGYRLAYEVIDDEIVVYVLAIGK
RDKDAVYKKLASRFS

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9155.34 Da        Isoelectric Point: 3.9840

>AT296744 WP_017038856.1 NZ_OX411212:1482563-1482814 [Vibrio campbellii]
MRQVLADCSASISELKKNPTALLNEADGSAIAILNHNKPAAYLVPAETYEFLMDMLDDYELAKLVESRRGELSEAVEVDI
DDL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1E5BHG0

Antitoxin

Source ID Structure
AlphaFold DB A0A4Y8W958

References