Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 2260315..2260895 Replicon chromosome
Accession NZ_OX365700
Organism Nitrospira sp. DNF

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag QWI75_RS10665 Protein ID WP_289268562.1
Coordinates 2260315..2260656 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag QWI75_RS10670 Protein ID WP_289268563.1
Coordinates 2260653..2260895 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QWI75_RS10650 (DNFV4_02214) 2255600..2257738 + 2139 WP_289268559.1 DUF5050 domain-containing protein -
QWI75_RS10655 (DNFV4_02215) 2258165..2259034 + 870 WP_289268560.1 hypothetical protein -
QWI75_RS10660 (DNFV4_02216) 2259146..2259844 + 699 WP_289268561.1 hypothetical protein -
QWI75_RS10665 (DNFV4_02217) 2260315..2260656 - 342 WP_289268562.1 endoribonuclease MazF Toxin
QWI75_RS10670 (DNFV4_02218) 2260653..2260895 - 243 WP_289268563.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
QWI75_RS10685 (DNFV4_02222) 2263166..2264017 + 852 WP_289268565.1 4'-phosphopantetheinyl transferase superfamily protein -
QWI75_RS10690 (DNFV4_02223) 2264034..2264534 - 501 WP_289268566.1 tRNA adenosine(34) deaminase TadA -
QWI75_RS10695 (DNFV4_02224) 2264732..2265895 - 1164 WP_289268567.1 nucleotidyltransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(7-113)

Antitoxin

Antitoxin PemI-like

(1-80)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12524.56 Da        Isoelectric Point: 10.2966

>T296742 WP_289268562.1 NZ_OX365700:c2260656-2260315 [Nitrospira sp. DNF]
VKSRRPYVPDRGDIVWLQFSPQVGHEQAGHRPALVLSPASYNRRSGLMLCCPMTSQRKDYPFEVVIPGEPDQKSVVLADQ
VKSLDWKARKAVKKGTAPVGVIADTLSKLQTLL

Download         Length: 342 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9137.71 Da        Isoelectric Point: 11.5088

>AT296742 WP_289268563.1 NZ_OX365700:c2260895-2260653 [Nitrospira sp. DNF]
MKTTAQKWGNSLAIRVPKSIAQQAGLKVKDDLEIEVRKGALVLRPHLRRVYRLEDLVRRITPRNVHREIDFGGPVGREAL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References