Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicB-HicA
Location 846851..847299 Replicon chromosome
Accession NZ_OX365700
Organism Nitrospira sp. DNF

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag QWI75_RS04070 Protein ID WP_289267412.1
Coordinates 847066..847299 (+) Length 78 a.a.

Antitoxin (Protein)


Gene name hicA Uniprot ID -
Locus tag QWI75_RS04065 Protein ID WP_289267411.1
Coordinates 846851..847069 (+) Length 73 a.a.

Genomic Context

QWI75_RS04055QWI75_RS04065QWI75_RS04070QWI75_RS04050QWI75_RS04060QWI75_RS04075QWI75_RS04080QWI75_RS04085
Location: 846117..846308 (192 bp)
Type: Others
Protein ID: WP_289267409.1
Location: 846851..847069 (219 bp)
Type: Antitoxin
Protein ID: WP_289267411.1
Location: 847066..847299 (234 bp)
Type: Toxin
Protein ID: WP_289267412.1
Location: 844020..845603 (1584 bp)
Type: Others
Protein ID: WP_289267408.1
Location: 846295..846681 (387 bp)
Type: Others
Protein ID: WP_289267410.1
Location: 847442..849388 (1947 bp)
Type: Others
Protein ID: WP_289267413.1
Location: 849920..850288 (369 bp)
Type: Others
Protein ID: WP_289267414.1
Location: 850852..851811 (960 bp)
Type: Others
Protein ID: WP_289267415.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QWI75_RS04050 (DNFV4_00845)844020..845603-1584WP_289267408.1PAS domain S-box protein-
QWI75_RS04055 (DNFV4_00847)846117..846308+192WP_289267409.1hypothetical protein-
QWI75_RS04060846295..846681-387WP_289267410.1hypothetical protein-
QWI75_RS04065 (DNFV4_00849)846851..847069+219WP_289267411.1type II toxin-antitoxin system HicB family antitoxinAntitoxin
QWI75_RS04070 (DNFV4_00850)847066..847299+234WP_289267412.1type II toxin-antitoxin system HicA family toxinToxin
QWI75_RS04075 (DNFV4_00851)847442..849388-1947WP_289267413.1TonB-dependent receptor-
QWI75_RS04080 (DNFV4_00852)849920..850288-369WP_289267414.1hypothetical protein-
QWI75_RS04085 (DNFV4_00854)850852..851811-960WP_289267415.1hypothetical protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(10-64)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(5-67)


Sequences

Toxin        


Download         Length: 78 a.a.        Molecular weight: 9036.46 Da        Isoelectric Point: 10.0936

>T296741 WP_289267412.1 NZ_OX365700:847066-847299 [Nitrospira sp. DNF]
MTRLSIVDCKTMEKILLRLGFASVRQKGSHVFYRHPDGRTTTVPHHPSQDLARPLVREILREIDLTPEQFRRELDNL

Download         Length: 234 bp

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8127.21 Da        Isoelectric Point: 4.3753

>AT296741 WP_289267411.1 NZ_OX365700:846851-847069 [Nitrospira sp. DNF]
MRTFAAYLEWDPDTQMYVGFVPGISGAHTQGKTLDELHKNLKEVLELCLEEYRASGEELPRFVGLQQIEVAG

Download         Length: 219 bp


Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References