296739

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 3266066..3267723 Replicon chromosome
Accession NZ_OX359243
Organism Alteromonas macleodii isolate Alteromonas macleodii BGP9

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag ALTBGP14_RS14175 Protein ID WP_231513104.1
Coordinates 3266066..3266659 (+) Length 198 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag ALTBGP14_RS14180 Protein ID WP_061486365.1
Coordinates 3266659..3267723 (+) Length 355 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ALTBGP14_RS14160 (ALTBGP9_02869) 3262067..3263578 + 1512 WP_061486361.1 serine hydrolase domain-containing protein -
ALTBGP14_RS14165 (ALTBGP9_02870) 3264019..3264804 - 786 WP_061486362.1 BRO family protein -
ALTBGP14_RS14170 (ALTBGP9_02871) 3265435..3266010 + 576 WP_061486363.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
ALTBGP14_RS14175 (ALTBGP9_02872) 3266066..3266659 + 594 WP_231513104.1 DUF4433 domain-containing protein Toxin
ALTBGP14_RS14180 (ALTBGP9_02873) 3266659..3267723 + 1065 WP_061486365.1 macro domain-containing protein Antitoxin
ALTBGP14_RS14185 (ALTBGP9_02874) 3268085..3270982 - 2898 WP_156079132.1 aminomethyl-transferring glycine dehydrogenase -
ALTBGP14_RS14190 (ALTBGP9_02875) 3271104..3271493 - 390 WP_014950360.1 glycine cleavage system protein GcvH -
ALTBGP14_RS14195 (ALTBGP9_02876) 3271545..3272624 - 1080 WP_156078713.1 glycine cleavage system aminomethyltransferase GcvT -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(1-197)

Antitoxin

Macro domain

(18-128)


Sequences

Toxin        


Download         Length: 198 a.a.        Molecular weight: 22882.97 Da        Isoelectric Point: 6.9648

>T296739 WP_231513104.1 NZ_OX359243:3266066-3266659 [Alteromonas macleodii]
VHRNNIPWILDNGLYCGNSHVQSPNWEAIGNSELIQKRATHPVPISPFGSLNDYVPFYFTPFSPMLLNIKSGRGVKQRAN
EDIVILVSSLHKVEQLNLDFVYTDMHAYYQWASFYSDLNHLGEVDWPILQTRNFARDLNDPAKFERYQAEALVKQHCPIN
ALVGIACYNTRVEQELKHHIQQRNMNLDVIVRPGWYF

Download         Length: 594 bp

Antitoxin


Download         Length: 355 a.a.        Molecular weight: 40015.25 Da        Isoelectric Point: 8.0792

>AT296739 WP_061486365.1 NZ_OX359243:3266659-3267723 [Alteromonas macleodii]
MITYTQGNLLEAQVEALVNTVNTVGVMGKGIALMFKERFPKNMAEYASACKAKQVNTGKMFVTETSELMGPKWIVNFPTK
QHWRAKSKMEWIQEGLIDLRYFLENNNVRSIAIPPLGAGQGGLAWPDVKMEIEKALSDIKTTNIIVFEPTSKYQNVAKAS
GVKKLTPARALVAELVRRYWILGMECSLLEIQKLAWFLQRTIEKRGLKNELKLKFEANYYGPYANNLDHLLNALDGSYLK
SDKRIPDCDPLDVIWFNESEKQKISTYLNTEAKEYLPALEGATQVISGFESPFGLELLSTVDWLVTNQGCERTVESIKEG
IANWPAGAKWAQRKFNLFSNKDIEFALTNLEILA

Download         Length: 1065 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References