Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 300423..300568 Replicon chromosome
Accession NZ_OX359182
Organism Klebsiella pneumoniae strain KP34 isolate 2018-347802-001-01

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 300430..300532 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 300423..300568 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM989_RS01450 295955..297388 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
OM989_RS01455 297504..297743 + 240 WP_002911393.1 YebV family protein -
OM989_RS01460 297841..298032 + 192 WP_002911395.1 YebW family protein -
OM989_RS01465 298029..298682 - 654 WP_004891053.1 protein-serine/threonine phosphatase -
OM989_RS01470 298839..299807 + 969 WP_004151446.1 VirK/YbjX family protein -
OM989_RS01475 299912..300055 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 300423..300568 + 146 - - Antitoxin
- 300430..300532 - 103 - - Toxin
OM989_RS01480 300691..301029 - 339 WP_002911404.1 YebY family protein -
OM989_RS01485 301046..301915 - 870 WP_032435031.1 copper homeostasis membrane protein CopD -
OM989_RS01490 301919..302293 - 375 WP_004151448.1 CopC domain-containing protein YobA -
OM989_RS01495 302406..302636 + 231 WP_002911406.1 DNA polymerase III subunit theta -
OM989_RS01500 302715..303374 + 660 WP_032435029.1 exodeoxyribonuclease X -
OM989_RS01505 303378..305438 - 2061 WP_004148850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T296710 NZ_OX359182:c300532-300430 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT296710 NZ_OX359182:300423-300568 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References