Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | abiEi-abiEii/AbiEii-AbiEi |
Location | 740032..741464 | Replicon | chromosome |
Accession | NZ_OX352831 | ||
Organism | Streptococcus suis isolate 861160_dxerD_hsdSE |
Toxin (Protein)
Gene name | abiEi | Uniprot ID | - |
Locus tag | QNH78_RS03780 | Protein ID | WP_074390209.1 |
Coordinates | 740032..740877 (-) | Length | 282 a.a. |
Antitoxin (Protein)
Gene name | abiEii | Uniprot ID | Q8DZ36 |
Locus tag | QNH78_RS03785 | Protein ID | WP_000037239.1 |
Coordinates | 740874..741464 (-) | Length | 197 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QNH78_RS03775 | 737168..739969 | + | 2802 | WP_074400605.1 | phage tail tip lysozyme | - |
QNH78_RS03780 | 740032..740877 | - | 846 | WP_074390209.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
QNH78_RS03785 | 740874..741464 | - | 591 | WP_000037239.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Integrative and Conjugative Element | - | neuB | 682299..786157 | 103858 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 282 a.a. Molecular weight: 32524.20 Da Isoelectric Point: 5.2246
>T296653 WP_074390209.1 NZ_OX352831:c740877-740032 [Streptococcus suis]
MNKAKLTALCHKISKNTGLTFNSVMTYYFLEVILKKLSQSSYSNHYIFKGGFLLSNVIGVESRSTVDIDFLFHQITLSEE
TVKQQLKEILADSEEGISFVIQSITAIKESDDYGGYRATILCQLENIKQVIHLDIATGDVVTPQPITYDYKAIFDEDNFP
IIAYTIETILAEKLQTIYSRNFLNSRSKDFYDVYILSKLKKEDIDFIQLKNACQRTFSYRETELDFEKIIELLERFKSDP
IQNKQWQNYSKKYSYTKGISLADVLDEMIRFITVLISINSD
MNKAKLTALCHKISKNTGLTFNSVMTYYFLEVILKKLSQSSYSNHYIFKGGFLLSNVIGVESRSTVDIDFLFHQITLSEE
TVKQQLKEILADSEEGISFVIQSITAIKESDDYGGYRATILCQLENIKQVIHLDIATGDVVTPQPITYDYKAIFDEDNFP
IIAYTIETILAEKLQTIYSRNFLNSRSKDFYDVYILSKLKKEDIDFIQLKNACQRTFSYRETELDFEKIIELLERFKSDP
IQNKQWQNYSKKYSYTKGISLADVLDEMIRFITVLISINSD
Download Length: 846 bp
Antitoxin
Download Length: 197 a.a. Molecular weight: 23074.63 Da Isoelectric Point: 7.8056
>AT296653 WP_000037239.1 NZ_OX352831:c741464-740874 [Streptococcus suis]
MSKKEILLDFIEKNNGIVTNKDCKALGIPTIYLTRLEKEGIIFRVEKGIFLTQNGDYDEYYFFQYRFPKAIFSYISALYL
QQFTDEIPQYFDVTVPRGYRFNTPPANLNIHFVSKEYSELGMTTVPTPMGNNVRVYDFERIICDFVIHREKIDSELFVKT
LQSYGNYPKKNLAKLYEYATKMNTLEKVKQTLEVLI
MSKKEILLDFIEKNNGIVTNKDCKALGIPTIYLTRLEKEGIIFRVEKGIFLTQNGDYDEYYFFQYRFPKAIFSYISALYL
QQFTDEIPQYFDVTVPRGYRFNTPPANLNIHFVSKEYSELGMTTVPTPMGNNVRVYDFERIICDFVIHREKIDSELFVKT
LQSYGNYPKKNLAKLYEYATKMNTLEKVKQTLEVLI
Download Length: 591 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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