Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | parDE/RelB(antitoxin) |
Location | 1956170..1956776 | Replicon | chromosome |
Accession | NZ_OX352806 | ||
Organism | Streptococcus suis isolate 861160_dxerD_hsdSA |
Toxin (Protein)
Gene name | parE | Uniprot ID | A0A0Z8ZB64 |
Locus tag | QNH74_RS09555 | Protein ID | WP_012775364.1 |
Coordinates | 1956170..1956499 (-) | Length | 110 a.a. |
Antitoxin (Protein)
Gene name | parD | Uniprot ID | D5AKB4 |
Locus tag | QNH74_RS09560 | Protein ID | WP_012028535.1 |
Coordinates | 1956489..1956776 (-) | Length | 96 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QNH74_RS09525 | 1953025..1953498 | - | 474 | WP_024378560.1 | IS200/IS605 family transposase | - |
QNH74_RS09530 | 1953678..1954550 | - | 873 | WP_024387385.1 | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA | - |
QNH74_RS09535 | 1954569..1955099 | - | 531 | WP_074390182.1 | DUF1697 domain-containing protein | - |
QNH74_RS09540 | 1955113..1955370 | - | 258 | WP_012775363.1 | Txe/YoeB family addiction module toxin | - |
QNH74_RS09545 | 1955372..1955632 | - | 261 | WP_002939010.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
QNH74_RS09550 | 1955708..1956163 | - | 456 | WP_074390181.1 | 8-oxo-dGTP diphosphatase | - |
QNH74_RS09555 | 1956170..1956499 | - | 330 | WP_012775364.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
QNH74_RS09560 | 1956489..1956776 | - | 288 | WP_012028535.1 | hypothetical protein | Antitoxin |
QNH74_RS09565 | 1956874..1957242 | - | 369 | WP_012775453.1 | hypothetical protein | - |
QNH74_RS09570 | 1957235..1957804 | - | 570 | WP_012775700.1 | ribonuclease M5 | - |
QNH74_RS09575 | 1957788..1958570 | - | 783 | WP_012028536.1 | TatD family hydrolase | - |
QNH74_RS09580 | 1958677..1958814 | - | 138 | WP_002939016.1 | 50S ribosomal protein L34 | - |
QNH74_RS09585 | 1958982..1959977 | - | 996 | WP_012775367.1 | RNA-binding cell elongation regulator Jag/EloR | - |
QNH74_RS09590 | 1959997..1960809 | - | 813 | WP_012027897.1 | YidC/Oxa1 family membrane protein insertase | - |
QNH74_RS09595 | 1960793..1961152 | - | 360 | WP_004194560.1 | ribonuclease P protein component | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 1931690..1958570 | 26880 | |
- | flank | IS/Tn | - | - | 1953025..1953498 | 473 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 110 a.a. Molecular weight: 12562.52 Da Isoelectric Point: 7.1991
>T296650 WP_012775364.1 NZ_OX352806:c1956499-1956170 [Streptococcus suis]
MEFESYSVILAPAVEKELAVIYAYFSEQFSEEIAKRRIGMIVEALESLQIFPERGFNADNRFGKQIDPPHLTRGYVVGKD
YIALYRVVKNEVRVGHLFATKSDYVKLLK
MEFESYSVILAPAVEKELAVIYAYFSEQFSEEIAKRRIGMIVEALESLQIFPERGFNADNRFGKQIDPPHLTRGYVVGKD
YIALYRVVKNEVRVGHLFATKSDYVKLLK
Download Length: 330 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0Z8ZB64 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0Z9A6F4 |