Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 5040570..5041158 Replicon chromosome
Accession NZ_OX352324
Organism Pseudomonas sp. MM221

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag OM991_RS23600 Protein ID WP_264360335.1
Coordinates 5040570..5040872 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag OM991_RS23605 Protein ID WP_264360336.1
Coordinates 5040865..5041158 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM991_RS23575 5036414..5036542 - 129 WP_009683677.1 PA1414 family protein -
OM991_RS23580 (GLGCALEP_04900) 5036667..5037559 - 893 Protein_4631 LysR substrate-binding domain-containing protein -
OM991_RS23585 (GLGCALEP_04901) 5037666..5038835 + 1170 WP_264360332.1 MFS transporter -
OM991_RS23590 (GLGCALEP_04902) 5038963..5039889 - 927 WP_264360333.1 DMT family transporter -
OM991_RS23595 (GLGCALEP_04903) 5039996..5040391 - 396 WP_264360334.1 transcriptional regulator -
OM991_RS23600 5040570..5040872 + 303 WP_264360335.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OM991_RS23605 (GLGCALEP_04904) 5040865..5041158 + 294 WP_264360336.1 putative addiction module antidote protein Antitoxin
OM991_RS23610 (GLGCALEP_04905) 5041244..5041516 + 273 WP_105946027.1 hypothetical protein -
OM991_RS23615 (GLGCALEP_04907) 5041637..5042996 - 1360 Protein_4638 DEAD/DEAH box helicase -
OM991_RS23620 (GLGCALEP_04908) 5043100..5044398 + 1299 WP_264360337.1 mechanosensitive ion channel family protein -
OM991_RS23625 (GLGCALEP_04909) 5044513..5045448 - 936 WP_264360338.1 AEC family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(5-95)

Antitoxin

Uncharacterized protein HI1420

(7-93)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11421.10 Da        Isoelectric Point: 10.8773

>T296640 WP_264360335.1 NZ_OX352324:5040570-5040872 [Pseudomonas sp. MM221]
MKKIESSSFRHWVTGLRDVNARARIISRINRLMEGLPGDVSPVGQGISELRIHYGPGYRVYFHQVGSTFVILLCGGEKSS
QQRDIKTAHQILRSWRIQND

Download         Length: 303 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10459.92 Da        Isoelectric Point: 4.7906

>AT296640 WP_264360336.1 NZ_OX352324:5040865-5041158 [Pseudomonas sp. MM221]
MTETFSEFDPAEYLTTPEAIALFMTDALETGDAGYVAKAVGVVARAKGMSELAKETGLSREQLYRSFSEHGNPTLKSFLT
VMKALGIDMTARPHLAG

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References