Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4196127..4196643 Replicon chromosome
Accession NZ_OX352324
Organism Pseudomonas sp. MM221

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OM991_RS19505 Protein ID WP_264359765.1
Coordinates 4196127..4196408 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OM991_RS19510 Protein ID WP_264359766.1
Coordinates 4196398..4196643 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM991_RS19490 (GLGCALEP_04051) 4192465..4193706 - 1242 WP_264359763.1 Zn-dependent hydrolase -
OM991_RS19495 (GLGCALEP_04052) 4193737..4195041 - 1305 WP_264359764.1 MFS transporter -
OM991_RS19500 (GLGCALEP_04054) 4195223..4196130 + 908 Protein_3829 LysR family transcriptional regulator -
OM991_RS19505 (GLGCALEP_04055) 4196127..4196408 - 282 WP_264359765.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OM991_RS19510 (GLGCALEP_04056) 4196398..4196643 - 246 WP_264359766.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OM991_RS19515 (GLGCALEP_04057) 4196863..4197660 + 798 WP_264359767.1 SDR family oxidoreductase -
OM991_RS19520 (GLGCALEP_04058) 4197682..4198089 + 408 WP_264359768.1 SRPBCC family protein -
OM991_RS19525 (GLGCALEP_04059) 4198208..4199194 + 987 WP_264359769.1 zinc-binding dehydrogenase -
OM991_RS19530 (GLGCALEP_04060) 4199302..4199843 + 542 Protein_3835 WYL domain-containing protein -
OM991_RS19535 (GLGCALEP_04062) 4199941..4200876 + 936 WP_264359770.1 cyclase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-76)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10853.72 Da        Isoelectric Point: 10.7594

>T296638 WP_264359765.1 NZ_OX352324:c4196408-4196127 [Pseudomonas sp. MM221]
MTYKLEFLPSALKEWGKLGHTVREQIKKKLGERLQSPKVQADALRDLANHYKIKLKASGYRLVYRVEDERIVVVVVSVGK
RERSEVYRAAQKR

Download         Length: 282 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8763.21 Da        Isoelectric Point: 4.3611

>AT296638 WP_264359766.1 NZ_OX352324:c4196643-4196398 [Pseudomonas sp. MM221]
MQNIFADVAVSVSELKKNPSAVMTGAAGMPVAVLNHNRVMGYMVPAELYEAMMERLEDLELSELAKARLGEKGVPVSLDD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References