Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 1256400..1257084 Replicon chromosome
Accession NZ_OX352324
Organism Pseudomonas sp. MM221

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag OM991_RS05805 Protein ID WP_264361875.1
Coordinates 1256713..1257084 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag OM991_RS05800 Protein ID WP_264361874.1
Coordinates 1256400..1256720 (-) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM991_RS05775 (GLGCALEP_01209) 1252587..1252988 + 402 WP_086979063.1 FagA protein -
OM991_RS05780 1252981..1254355 + 1375 Protein_1120 class II fumarate hydratase -
OM991_RS05785 (GLGCALEP_01212) 1254384..1254845 + 462 WP_264361872.1 DUF2753 domain-containing protein -
OM991_RS05790 (GLGCALEP_01213) 1254847..1255458 + 612 WP_264361873.1 superoxide dismutase -
OM991_RS05795 (GLGCALEP_01214) 1255470..1256363 + 894 WP_234227567.1 ZIP family metal transporter -
OM991_RS05800 (GLGCALEP_01215) 1256400..1256720 - 321 WP_264361874.1 helix-turn-helix transcriptional regulator Antitoxin
OM991_RS05805 (GLGCALEP_01216) 1256713..1257084 - 372 WP_264361875.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OM991_RS05810 (GLGCALEP_01217) 1257173..1257445 - 273 WP_010952144.1 HPr family phosphocarrier protein -
OM991_RS05815 (GLGCALEP_01218) 1257465..1258319 - 855 WP_264361876.1 RNase adapter RapZ -
OM991_RS05820 (GLGCALEP_01219) 1258322..1258786 - 465 WP_019471369.1 PTS IIA-like nitrogen regulatory protein PtsN -
OM991_RS05825 (GLGCALEP_01220) 1258799..1259107 - 309 WP_016485037.1 ribosome-associated translation inhibitor RaiA -
OM991_RS05830 (GLGCALEP_01221) 1259187..1260680 - 1494 WP_264361877.1 RNA polymerase factor sigma-54 -
OM991_RS05835 (GLGCALEP_01222) 1260857..1261582 - 726 WP_003255132.1 LPS export ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(18-111)

Antitoxin

HigA2-like, helix-turn-helix domain

(11-90)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13667.52 Da        Isoelectric Point: 9.4692

>T296635 WP_264361875.1 NZ_OX352324:c1257084-1256713 [Pseudomonas sp. MM221]
MDALKRIRALYWVGSSKKDLQALPEDVQDIFGFALHLAQEGGKHQQTKCLKGFSGAGVLEVMEDHNRNTYRAVYTVSFGS
AVYVLHCFQKKSTSGIKTSSHDIALIRSRLKLAEAHSRGDTND

Download         Length: 372 bp

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11605.64 Da        Isoelectric Point: 10.2100

>AT296635 WP_264361874.1 NZ_OX352324:c1256720-1256400 [Pseudomonas sp. MM221]
MTEIETGSGNVYADLNSADANEMLVKAQLASKICSIIKARHLTQVQAAAVLGLPQPKVSEMMRGKFRGISETKMIDCLAR
LGRDIQIVIKPAPRSRREGRVEVIIT

Download         Length: 321 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References