Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 5041685..5042273 Replicon chromosome
Accession NZ_OX352322
Organism Pseudomonas sp. MM223

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag ONI07_RS23440 Protein ID WP_264360335.1
Coordinates 5041685..5041987 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag ONI07_RS23445 Protein ID WP_264360336.1
Coordinates 5041980..5042273 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ONI07_RS23415 5037526..5037654 - 129 WP_009683677.1 PA1414 family protein -
ONI07_RS23420 (DBADOPDK_04781) 5037779..5038672 - 894 WP_264387151.1 LysR family transcriptional regulator -
ONI07_RS23425 (DBADOPDK_04782) 5038779..5039948 + 1170 WP_264360332.1 MFS transporter -
ONI07_RS23430 (DBADOPDK_04783) 5040078..5041004 - 927 WP_264360333.1 DMT family transporter -
ONI07_RS23435 (DBADOPDK_04784) 5041111..5041506 - 396 WP_264360334.1 transcriptional regulator -
ONI07_RS23440 5041685..5041987 + 303 WP_264360335.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ONI07_RS23445 (DBADOPDK_04785) 5041980..5042273 + 294 WP_264360336.1 putative addiction module antidote protein Antitoxin
ONI07_RS23450 (DBADOPDK_04786) 5042359..5042631 + 273 WP_105946027.1 hypothetical protein -
ONI07_RS23455 (DBADOPDK_04788) 5042752..5044112 - 1361 Protein_4609 DEAD/DEAH box helicase -
ONI07_RS23460 (DBADOPDK_04789) 5044216..5045514 + 1299 WP_264360337.1 mechanosensitive ion channel family protein -
ONI07_RS23465 (DBADOPDK_04790) 5045629..5046564 - 936 WP_264360338.1 AEC family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(5-95)

Antitoxin

Uncharacterized protein HI1420

(7-93)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11421.10 Da        Isoelectric Point: 10.8773

>T296630 WP_264360335.1 NZ_OX352322:5041685-5041987 [Pseudomonas sp. MM223]
MKKIESSSFRHWVTGLRDVNARARIISRINRLMEGLPGDVSPVGQGISELRIHYGPGYRVYFHQVGSTFVILLCGGEKSS
QQRDIKTAHQILRSWRIQND

Download         Length: 303 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10459.92 Da        Isoelectric Point: 4.7906

>AT296630 WP_264360336.1 NZ_OX352322:5041980-5042273 [Pseudomonas sp. MM223]
MTETFSEFDPAEYLTTPEAIALFMTDALETGDAGYVAKAVGVVARAKGMSELAKETGLSREQLYRSFSEHGNPTLKSFLT
VMKALGIDMTARPHLAG

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References