Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /DUF1778(antitoxin)
Location 548454..549220 Replicon chromosome
Accession NZ_OX352320
Organism Rheinheimera sp. MM224

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag OM978_RS02680 Protein ID WP_264346911.1
Coordinates 548723..549220 (+) Length 166 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag OM978_RS02675 Protein ID WP_264345379.1
Coordinates 548454..548726 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM978_RS02645 (JAMGFMIE_00533) 543678..544232 - 555 WP_264345367.1 DUF805 domain-containing protein -
OM978_RS02650 (JAMGFMIE_00534) 544355..544729 - 375 WP_264345369.1 VOC family protein -
OM978_RS02655 (JAMGFMIE_00535) 544756..545190 - 435 WP_264345371.1 hypothetical protein -
OM978_RS02660 (JAMGFMIE_00536) 545244..545627 - 384 WP_264345373.1 hypothetical protein -
OM978_RS02665 (JAMGFMIE_00537) 545655..546284 - 630 WP_264345375.1 glutathione S-transferase -
OM978_RS02670 (JAMGFMIE_00538) 546416..548200 - 1785 WP_264345377.1 DUF885 domain-containing protein -
OM978_RS02675 (JAMGFMIE_00539) 548454..548726 + 273 WP_264345379.1 DUF1778 domain-containing protein Antitoxin
OM978_RS02680 (JAMGFMIE_00540) 548723..549220 + 498 WP_264346911.1 GNAT family N-acetyltransferase Toxin
OM978_RS02685 (JAMGFMIE_00541) 549238..550437 - 1200 WP_264345381.1 organoarsenical effux MFS transporter ArsJ -
OM978_RS02690 (JAMGFMIE_00542) 550460..551473 - 1014 WP_264345383.1 ArsJ-associated glyceraldehyde-3-phosphate dehydrogenase -
OM978_RS02695 (JAMGFMIE_00543) 551505..551855 - 351 WP_264345385.1 metalloregulator ArsR/SmtB family transcription factor -
OM978_RS02700 (JAMGFMIE_00544) 551986..552528 + 543 WP_264345387.1 PH domain-containing protein -
OM978_RS02705 (JAMGFMIE_00545) 552515..553999 + 1485 WP_264345389.1 PH domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(86-150)

Antitoxin

Vibrio phage ICP1, Orf50

(7-85)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 18504.25 Da        Isoelectric Point: 9.5997

>T296620 WP_264346911.1 NZ_OX352320:548723-549220 [Rheinheimera sp. MM224]
IMQTVLLDKSKHDRNRFNCGIDALNNYLKVMASQQSKKDNTRTFVLEDKANPQHIVGFYTLTMTPIDIQSLPASLQKKHQ
SSTSGGLIARLAVDERYKGQKTGEWMLIDAVKKLLQASDAVGFPIVIVDAKDGAKGFYQKYGFRCFEDSEHKLFITIADV
RASFG

Download         Length: 498 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9733.20 Da        Isoelectric Point: 8.6808

>AT296620 WP_264345379.1 NZ_OX352320:548454-548726 [Rheinheimera sp. MM224]
MTTTPPRITARVDAETQNLLSKAAAITGVSSINSFVLSAAVEKAKQIIEREQTLKLSQRDAMLLMDALDNPATVHPHLAA
AFARYEGKVQ

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References