Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 3212972..3213564 Replicon chromosome
Accession NZ_OX352319
Organism Pseudomonas sp. MM227

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag ONG87_RS14505 Protein ID WP_264381517.1
Coordinates 3213193..3213564 (+) Length 124 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag ONG87_RS14500 Protein ID WP_192138019.1
Coordinates 3212972..3213199 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ONG87_RS14480 (AHFPHNDE_02883) 3208366..3209538 + 1173 WP_264382864.1 2-methylaconitate cis-trans isomerase PrpF -
ONG87_RS14485 (AHFPHNDE_02884) 3209535..3210263 + 729 WP_264381516.1 transporter substrate-binding domain-containing protein -
ONG87_RS14490 (AHFPHNDE_02885) 3210433..3212076 + 1644 WP_122801094.1 acetolactate synthase large subunit -
ONG87_RS14495 (AHFPHNDE_02886) 3212235..3212795 - 561 WP_264382865.1 MFS transporter -
ONG87_RS14500 (AHFPHNDE_02887) 3212972..3213199 + 228 WP_192138019.1 ribbon-helix-helix protein, CopG family Antitoxin
ONG87_RS14505 (AHFPHNDE_02888) 3213193..3213564 + 372 WP_264381517.1 type II toxin-antitoxin system VapC family toxin Toxin
ONG87_RS14510 3213788..3213931 - 144 Protein_2843 transposase -
ONG87_RS14515 (AHFPHNDE_02889) 3213997..3214293 - 297 WP_264381518.1 DUF1330 domain-containing protein -
ONG87_RS14520 3214394..3214852 - 459 WP_264381519.1 cupin domain-containing protein -
ONG87_RS14525 (AHFPHNDE_02890) 3214959..3216359 - 1401 WP_264381520.1 GntP family permease -
ONG87_RS14530 (AHFPHNDE_02891) 3216444..3217223 - 780 WP_264381521.1 SDR family NAD(P)-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3209535..3220481 10946


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-112)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-39)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13860.00 Da        Isoelectric Point: 6.2158

>T296619 WP_264381517.1 NZ_OX352319:3213193-3213564 [Pseudomonas sp. MM227]
MVRSLFDTNILIDHLSGRPLAEQVIHAAHRPMISLITYMEVLGGAGDAKEADTLRHWMGQQFEVVPVSLDIAHEAVLLRQ
QRRIELPDAIIWASSRLAGAVLVTRNTKDFPETELDVRVPYHL

Download         Length: 372 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8477.60 Da        Isoelectric Point: 4.5535

>AT296619 WP_192138019.1 NZ_OX352319:3212972-3213199 [Pseudomonas sp. MM227]
MSRILADLTPKQLEDLNQLASALDTSRAALIREAVATFVAVKNEELKHPAPDVFGLWRDRAVDGLAYEQELRNEW

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References