Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 219098..219614 Replicon chromosome
Accession NZ_OX352319
Organism Pseudomonas sp. MM227

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ONG87_RS00960 Protein ID WP_192102789.1
Coordinates 219327..219614 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ONG87_RS00955 Protein ID WP_122795873.1
Coordinates 219098..219337 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ONG87_RS00935 215757..216863 + 1107 Protein_179 FIST C-terminal domain-containing protein -
ONG87_RS00940 217284..217778 + 495 WP_244657432.1 methyl-accepting chemotaxis protein -
ONG87_RS00945 (AHFPHNDE_00186) 217832..218686 - 855 WP_264382051.1 LysR family transcriptional regulator -
ONG87_RS00950 (AHFPHNDE_00187) 218782..219015 + 234 WP_192056581.1 DUF1127 domain-containing protein -
ONG87_RS00955 (AHFPHNDE_00188) 219098..219337 + 240 WP_122795873.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
ONG87_RS00960 (AHFPHNDE_00189) 219327..219614 + 288 WP_192102789.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ONG87_RS00965 (AHFPHNDE_00190) 219788..220627 + 840 WP_264382052.1 alpha/beta hydrolase-fold protein -
ONG87_RS00970 (AHFPHNDE_00191) 220727..221224 + 498 WP_122480580.1 RNA polymerase sigma factor -
ONG87_RS00975 (AHFPHNDE_00192) 221221..222183 + 963 WP_264382053.1 FecR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 219098..227139 8041


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-66)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11144.99 Da        Isoelectric Point: 10.2588

>T296615 WP_192102789.1 NZ_OX352319:219327-219614 [Pseudomonas sp. MM227]
MTYSLEFDARALKEWHKLGDTVRQQLKKKLVAILLNPRNEANRLHGLPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAVDK
REREAVYRKAAERLS

Download         Length: 288 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9078.42 Da        Isoelectric Point: 5.1299

>AT296615 WP_122795873.1 NZ_OX352319:219098-219337 [Pseudomonas sp. MM227]
MASINIRIDDDLKARAYHELEKLGVTPSELMRQTLQYVAERGQLPFKSVLVTEDDEALLEKVRERLANPQRVKVSLNDL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References