296614

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 64342..64819 Replicon chromosome
Accession NZ_OX352319
Organism Pseudomonas sp. MM227

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag ONG87_RS00305 Protein ID WP_264382005.1
Coordinates 64553..64819 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag ONG87_RS00300 Protein ID WP_264382004.1
Coordinates 64342..64569 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ONG87_RS00280 (AHFPHNDE_00056) 59355..60026 - 672 WP_122480089.1 methionine ABC transporter permease -
ONG87_RS00285 (AHFPHNDE_00057) 60026..61033 - 1008 WP_192055222.1 methionine ABC transporter ATP-binding protein -
ONG87_RS00290 (AHFPHNDE_00058) 61317..63455 + 2139 WP_185794590.1 catalase HPII -
ONG87_RS00295 (AHFPHNDE_00059) 63452..64159 - 708 WP_192055224.1 PA5502 family lipoprotein -
ONG87_RS00300 (AHFPHNDE_00060) 64342..64569 + 228 WP_264382004.1 CopG family transcriptional regulator Antitoxin
ONG87_RS00305 (AHFPHNDE_00061) 64553..64819 + 267 WP_264382005.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ONG87_RS00310 (AHFPHNDE_00062) 64844..65626 - 783 WP_122480093.1 zinc ABC transporter permease subunit ZnuB -
ONG87_RS00315 (AHFPHNDE_00063) 65619..66389 - 771 WP_122480094.1 zinc ABC transporter ATP-binding protein ZnuC -
ONG87_RS00320 (AHFPHNDE_00064) 66389..66871 - 483 WP_122480095.1 Fur family transcriptional regulator -
ONG87_RS00325 (AHFPHNDE_00065) 66947..67858 + 912 WP_264382890.1 zinc ABC transporter substrate-binding protein -
ONG87_RS00330 (AHFPHNDE_00066) 67969..68919 - 951 WP_185794585.1 homoserine kinase -
ONG87_RS00335 (AHFPHNDE_00067) 68984..69271 - 288 WP_264382006.1 DUF2782 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10227.68 Da        Isoelectric Point: 9.6854

>T296614 WP_264382005.1 NZ_OX352319:64553-64819 [Pseudomonas sp. MM227]
MAWTIDYTDTARTQLRKLDKQTARRILDFMDERIGGRDDPRSTGKALTGPLGGLWRYRIEDFQVVCDIQDGALRVLVVQL
GNRREVYR

Download         Length: 267 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8488.49 Da        Isoelectric Point: 4.7824

>AT296614 WP_264382004.1 NZ_OX352319:64342-64569 [Pseudomonas sp. MM227]
MATSIRLAPETEQRLDFLASSTGRTKAYYLRQIIDNGLSDLEDYYLAAEVLERVRKGRETVHSAADVRKDLGLDD

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References