Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 206994..207480 Replicon chromosome
Accession NZ_OX346407
Organism Enterococcus cecorum isolate CIRMBP-1274

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QML77_RS01085 Protein ID WP_281956944.1
Coordinates 206994..207266 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QML77_RS01090 Protein ID WP_281956945.1
Coordinates 207253..207480 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QML77_RS01075 (CIRMBP1274_00211) 202740..205154 + 2415 WP_281956942.1 leucine--tRNA ligase -
QML77_RS01080 (CIRMBP1274_00212) 205321..206778 + 1458 WP_281956943.1 hypothetical protein -
QML77_RS01085 (CIRMBP1274_00213) 206994..207266 - 273 WP_281956944.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QML77_RS01090 (CIRMBP1274_00214) 207253..207480 - 228 WP_281956945.1 DUF6290 family protein Antitoxin
QML77_RS01095 (CIRMBP1274_00215) 207691..209949 + 2259 WP_281956946.1 bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB -
QML77_RS01100 (CIRMBP1274_00216) 209979..210419 - 441 WP_281956947.1 YueI family protein -
QML77_RS01105 (CIRMBP1274_00217) 210525..210929 + 405 WP_047242147.1 iron-sulfur cluster biosynthesis family protein -
QML77_RS01110 (CIRMBP1274_00218) 211110..211661 - 552 WP_281956948.1 biotin transporter BioY -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-88)

Antitoxin

Protein of unknown function DUF6290

(4-71)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10700.44 Da        Isoelectric Point: 10.6292

>T296613 WP_281956944.1 NZ_OX346407:c207266-206994 [Enterococcus cecorum]
MKKYNVALSERFKKEFRKLDKYTQKMIRGWIDKNLVGTSNPRIHGKSLTANRSGQWRYRIGDYRLICQIEDNELIILALT
VGHQREIYGK

Download         Length: 273 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8874.06 Da        Isoelectric Point: 4.5686

>AT296613 WP_281956945.1 NZ_OX346407:c207480-207253 [Enterococcus cecorum]
MAFFIRLSEKERKLAESYARLHAMSLGEAFKKALFERIEDEYDLVIAKEAYQDYVDSGHKLTPVAEFWRELDEEV

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References