296579

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 3369306..3370963 Replicon chromosome
Accession NZ_OX335040
Organism Alteromonas macleodii isolate Alteromonas macleodii 83-1

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag MIT1002_RS14590 Protein ID WP_231513104.1
Coordinates 3369306..3369899 (+) Length 198 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag MIT1002_RS14595 Protein ID WP_061486365.1
Coordinates 3369899..3370963 (+) Length 355 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MIT1002_RS14575 (ALT831_02952) 3365307..3366818 + 1512 WP_061486361.1 serine hydrolase domain-containing protein -
MIT1002_RS14580 (ALT831_02953) 3367259..3368044 - 786 WP_061486362.1 BRO family protein -
MIT1002_RS14585 (ALT831_02954) 3368675..3369250 + 576 WP_061486363.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
MIT1002_RS14590 (ALT831_02955) 3369306..3369899 + 594 WP_231513104.1 DUF4433 domain-containing protein Toxin
MIT1002_RS14595 (ALT831_02956) 3369899..3370963 + 1065 WP_061486365.1 macro domain-containing protein Antitoxin
MIT1002_RS14600 (ALT831_02957) 3371325..3374222 - 2898 WP_156079132.1 aminomethyl-transferring glycine dehydrogenase -
MIT1002_RS14605 (ALT831_02958) 3374344..3374733 - 390 WP_014950360.1 glycine cleavage system protein GcvH -
MIT1002_RS14610 (ALT831_02959) 3374785..3375864 - 1080 WP_156078713.1 glycine cleavage system aminomethyltransferase GcvT -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(1-197)

Antitoxin

Macro domain

(18-128)


Sequences

Toxin        


Download         Length: 198 a.a.        Molecular weight: 22882.97 Da        Isoelectric Point: 6.9648

>T296579 WP_231513104.1 NZ_OX335040:3369306-3369899 [Alteromonas macleodii]
VHRNNIPWILDNGLYCGNSHVQSPNWEAIGNSELIQKRATHPVPISPFGSLNDYVPFYFTPFSPMLLNIKSGRGVKQRAN
EDIVILVSSLHKVEQLNLDFVYTDMHAYYQWASFYSDLNHLGEVDWPILQTRNFARDLNDPAKFERYQAEALVKQHCPIN
ALVGIACYNTRVEQELKHHIQQRNMNLDVIVRPGWYF

Download         Length: 594 bp

Antitoxin


Download         Length: 355 a.a.        Molecular weight: 40015.25 Da        Isoelectric Point: 8.0792

>AT296579 WP_061486365.1 NZ_OX335040:3369899-3370963 [Alteromonas macleodii]
MITYTQGNLLEAQVEALVNTVNTVGVMGKGIALMFKERFPKNMAEYASACKAKQVNTGKMFVTETSELMGPKWIVNFPTK
QHWRAKSKMEWIQEGLIDLRYFLENNNVRSIAIPPLGAGQGGLAWPDVKMEIEKALSDIKTTNIIVFEPTSKYQNVAKAS
GVKKLTPARALVAELVRRYWILGMECSLLEIQKLAWFLQRTIEKRGLKNELKLKFEANYYGPYANNLDHLLNALDGSYLK
SDKRIPDCDPLDVIWFNESEKQKISTYLNTEAKEYLPALEGATQVISGFESPFGLELLSTVDWLVTNQGCERTVESIKEG
IANWPAGAKWAQRKFNLFSNKDIEFALTNLEILA

Download         Length: 1065 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References