Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2051024..2051169 Replicon chromosome
Accession NZ_OW970553
Organism Klebsiella pneumoniae isolate 147

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2051060..2051162 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2051024..2051169 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQV20_RS09970 2046154..2048214 + 2061 WP_004151449.1 oligopeptidase B -
LQV20_RS09975 2048218..2048877 - 660 WP_002911407.1 exodeoxyribonuclease X -
LQV20_RS09980 2048956..2049186 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LQV20_RS09985 2049299..2049673 + 375 WP_039819395.1 CopC domain-containing protein YobA -
LQV20_RS09990 2049677..2050546 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
LQV20_RS09995 2050563..2050901 + 339 WP_002911404.1 YebY family protein -
- 2051024..2051169 - 146 - - Antitoxin
- 2051060..2051162 + 103 - - Toxin
LQV20_RS10000 2051538..2051681 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
LQV20_RS10005 2051786..2052754 - 969 WP_014907334.1 VirK/YbjX family protein -
LQV20_RS10010 2052911..2053564 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
LQV20_RS10015 2053561..2053752 - 192 WP_002911395.1 YebW family protein -
LQV20_RS10020 2053850..2054089 - 240 WP_002911393.1 YebV family protein -
LQV20_RS10025 2054205..2055638 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T296473 NZ_OW970553:2051060-2051162 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT296473 NZ_OW970553:c2051169-2051024 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References