Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2042069..2042214 Replicon chromosome
Accession NZ_OW970530
Organism Klebsiella pneumoniae isolate 147

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2042105..2042207 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2042069..2042214 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQV07_RS09940 2037199..2039259 + 2061 WP_004151449.1 oligopeptidase B -
LQV07_RS09945 2039263..2039922 - 660 WP_002911407.1 exodeoxyribonuclease X -
LQV07_RS09950 2040001..2040231 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LQV07_RS09955 2040344..2040718 + 375 WP_039819395.1 CopC domain-containing protein YobA -
LQV07_RS09960 2040722..2041591 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
LQV07_RS09965 2041608..2041946 + 339 WP_002911404.1 YebY family protein -
- 2042069..2042214 - 146 - - Antitoxin
- 2042105..2042207 + 103 - - Toxin
LQV07_RS09970 2042583..2042726 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
LQV07_RS09975 2042831..2043799 - 969 WP_014907334.1 VirK/YbjX family protein -
LQV07_RS09980 2043956..2044609 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
LQV07_RS09985 2044606..2044797 - 192 WP_002911395.1 YebW family protein -
LQV07_RS09990 2044895..2045134 - 240 WP_002911393.1 YebV family protein -
LQV07_RS09995 2045250..2046683 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T296439 NZ_OW970530:2042105-2042207 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT296439 NZ_OW970530:c2042214-2042069 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References