Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2026794..2026939 Replicon chromosome
Accession NZ_OW970514
Organism Klebsiella pneumoniae isolate 147

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2026830..2026932 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2026794..2026939 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ358_RS09855 2021924..2023984 + 2061 WP_004151449.1 oligopeptidase B -
LQ358_RS09860 2023988..2024647 - 660 WP_002911407.1 exodeoxyribonuclease X -
LQ358_RS09865 2024726..2024956 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LQ358_RS09870 2025069..2025443 + 375 WP_039819395.1 CopC domain-containing protein YobA -
LQ358_RS09875 2025447..2026316 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
LQ358_RS09880 2026333..2026671 + 339 WP_002911404.1 YebY family protein -
- 2026794..2026939 - 146 - - Antitoxin
- 2026830..2026932 + 103 - - Toxin
LQ358_RS09885 2027308..2027451 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
LQ358_RS09890 2027556..2028524 - 969 WP_014907334.1 VirK/YbjX family protein -
LQ358_RS09895 2028681..2029334 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
LQ358_RS09900 2029331..2029522 - 192 WP_002911395.1 YebW family protein -
LQ358_RS09905 2029620..2029859 - 240 WP_002911393.1 YebV family protein -
LQ358_RS09910 2029975..2031408 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T296422 NZ_OW970514:2026830-2026932 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT296422 NZ_OW970514:c2026939-2026794 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References