Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2043212..2043357 Replicon chromosome
Accession NZ_OW970478
Organism Klebsiella pneumoniae isolate 147

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2043248..2043350 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2043212..2043357 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQV36_RS09950 2038342..2040402 + 2061 WP_004151449.1 oligopeptidase B -
LQV36_RS09955 2040406..2041065 - 660 WP_002911407.1 exodeoxyribonuclease X -
LQV36_RS09960 2041144..2041374 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LQV36_RS09965 2041487..2041861 + 375 WP_039819395.1 CopC domain-containing protein YobA -
LQV36_RS09970 2041865..2042734 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
LQV36_RS09975 2042751..2043089 + 339 WP_002911404.1 YebY family protein -
- 2043212..2043357 - 146 - - Antitoxin
- 2043248..2043350 + 103 - - Toxin
LQV36_RS09980 2043726..2043869 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
LQV36_RS09985 2043974..2044942 - 969 WP_014907334.1 VirK/YbjX family protein -
LQV36_RS09990 2045099..2045752 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
LQV36_RS09995 2045749..2045940 - 192 WP_002911395.1 YebW family protein -
LQV36_RS10000 2046038..2046277 - 240 WP_002911393.1 YebV family protein -
LQV36_RS10005 2046393..2047826 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T296374 NZ_OW970478:2043248-2043350 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT296374 NZ_OW970478:c2043357-2043212 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References