Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2045192..2045337 Replicon chromosome
Accession NZ_OW970452
Organism Klebsiella pneumoniae isolate 147

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2045228..2045330 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2045192..2045337 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQV13_RS09945 2040322..2042382 + 2061 WP_004151449.1 oligopeptidase B -
LQV13_RS09950 2042386..2043045 - 660 WP_002911407.1 exodeoxyribonuclease X -
LQV13_RS09955 2043124..2043354 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LQV13_RS09960 2043467..2043841 + 375 WP_039819395.1 CopC domain-containing protein YobA -
LQV13_RS09965 2043845..2044714 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
LQV13_RS09970 2044731..2045069 + 339 WP_002911404.1 YebY family protein -
- 2045192..2045337 - 146 - - Antitoxin
- 2045228..2045330 + 103 - - Toxin
LQV13_RS09975 2045706..2045849 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
LQV13_RS09980 2045954..2046922 - 969 WP_014907334.1 VirK/YbjX family protein -
LQV13_RS09985 2047079..2047732 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
LQV13_RS09990 2047729..2047920 - 192 WP_002911395.1 YebW family protein -
LQV13_RS09995 2048018..2048257 - 240 WP_002911393.1 YebV family protein -
LQV13_RS10000 2048373..2049806 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T296357 NZ_OW970452:2045228-2045330 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT296357 NZ_OW970452:c2045337-2045192 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References