Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2045840..2045985 Replicon chromosome
Accession NZ_OW970444
Organism Klebsiella pneumoniae isolate 101

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2045876..2045978 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2045840..2045985 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQV08_RS10040 2040970..2043030 + 2061 WP_004151449.1 oligopeptidase B -
LQV08_RS10045 2043034..2043693 - 660 WP_002911407.1 exodeoxyribonuclease X -
LQV08_RS10050 2043772..2044002 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LQV08_RS10055 2044115..2044489 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LQV08_RS10060 2044493..2045362 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
LQV08_RS10065 2045379..2045717 + 339 WP_002911404.1 YebY family protein -
- 2045840..2045985 - 146 - - Antitoxin
- 2045876..2045978 + 103 - - Toxin
LQV08_RS10070 2046353..2046496 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LQV08_RS10075 2046601..2047569 - 969 WP_004151446.1 VirK/YbjX family protein -
LQV08_RS10080 2047726..2048379 + 654 WP_032418800.1 protein-serine/threonine phosphatase -
LQV08_RS10085 2048376..2048567 - 192 WP_002911395.1 YebW family protein -
LQV08_RS10090 2048665..2048904 - 240 WP_002911393.1 YebV family protein -
LQV08_RS10095 2049020..2050453 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T296339 NZ_OW970444:2045876-2045978 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT296339 NZ_OW970444:c2045985-2045840 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References