Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2069207..2069352 Replicon chromosome
Accession NZ_OW970374
Organism Klebsiella pneumoniae isolate 101

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2069243..2069345 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2069207..2069352 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQV21_RS10145 2064337..2066397 + 2061 WP_004151449.1 oligopeptidase B -
LQV21_RS10150 2066401..2067060 - 660 WP_002911407.1 exodeoxyribonuclease X -
LQV21_RS10155 2067139..2067369 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LQV21_RS10160 2067482..2067856 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LQV21_RS10165 2067860..2068729 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
LQV21_RS10170 2068746..2069084 + 339 WP_002911404.1 YebY family protein -
- 2069207..2069352 - 146 - - Antitoxin
- 2069243..2069345 + 103 - - Toxin
LQV21_RS10175 2069720..2069863 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LQV21_RS10180 2069968..2070936 - 969 WP_004151446.1 VirK/YbjX family protein -
LQV21_RS10185 2071093..2071746 + 654 WP_032418800.1 protein-serine/threonine phosphatase -
LQV21_RS10190 2071743..2071934 - 192 WP_002911395.1 YebW family protein -
LQV21_RS10195 2072032..2072271 - 240 WP_002911393.1 YebV family protein -
LQV21_RS10200 2072387..2073820 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T296275 NZ_OW970374:2069243-2069345 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT296275 NZ_OW970374:c2069352-2069207 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References