Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2052398..2052543 Replicon chromosome
Accession NZ_OW970357
Organism Klebsiella pneumoniae isolate 147

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2052434..2052536 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2052398..2052543 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQV29_RS09985 2047528..2049588 + 2061 WP_004151449.1 oligopeptidase B -
LQV29_RS09990 2049592..2050251 - 660 WP_002911407.1 exodeoxyribonuclease X -
LQV29_RS09995 2050330..2050560 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LQV29_RS10000 2050673..2051047 + 375 WP_039819395.1 CopC domain-containing protein YobA -
LQV29_RS10005 2051051..2051920 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
LQV29_RS10010 2051937..2052275 + 339 WP_002911404.1 YebY family protein -
- 2052398..2052543 - 146 - - Antitoxin
- 2052434..2052536 + 103 - - Toxin
LQV29_RS10015 2052912..2053055 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
LQV29_RS10020 2053160..2054128 - 969 WP_014907334.1 VirK/YbjX family protein -
LQV29_RS10025 2054285..2054938 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
LQV29_RS10030 2054935..2055126 - 192 WP_002911395.1 YebW family protein -
LQV29_RS10035 2055224..2055463 - 240 WP_002911393.1 YebV family protein -
LQV29_RS10040 2055579..2057012 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T296244 NZ_OW970357:2052434-2052536 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT296244 NZ_OW970357:c2052543-2052398 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References