Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 2116147..2117708 Replicon chromosome
Accession NZ_OW970315
Organism Pantoea agglomerans strain DAPP-PG734

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag OOS96_RS09790 Protein ID WP_031592298.1
Coordinates 2116395..2117708 (+) Length 438 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag OOS96_RS09785 Protein ID WP_022625644.1
Coordinates 2116147..2116395 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OOS96_RS09765 (DAPPPG734_09930) 2111394..2113619 + 2226 WP_031592293.1 iron ABC transporter permease -
OOS96_RS09770 (DAPPPG734_09935) 2113616..2114677 + 1062 WP_031592294.1 ABC transporter ATP-binding protein -
OOS96_RS09775 (DAPPPG734_09940) 2114701..2115495 + 795 WP_031592295.1 inositol monophosphatase family protein -
OOS96_RS09780 (DAPPPG734_09945) 2115529..2115966 - 438 WP_031592296.1 GNAT family N-acetyltransferase -
OOS96_RS09785 (DAPPPG734_09950) 2116147..2116395 + 249 WP_022625644.1 type II toxin-antitoxin system antitoxin HipB Antitoxin
OOS96_RS09790 (DAPPPG734_09955) 2116395..2117708 + 1314 WP_031592298.1 type II toxin-antitoxin system HipA family toxin Toxin
OOS96_RS09795 (DAPPPG734_09960) 2117846..2118019 + 174 WP_230873490.1 type II toxin-antitoxin system MqsA family antitoxin -
OOS96_RS09800 (DAPPPG734_09965) 2118346..2119770 + 1425 WP_031592299.1 M24 family metallopeptidase -
OOS96_RS09805 (DAPPPG734_09970) 2119846..2121891 + 2046 WP_031592300.1 FUSC family protein -
OOS96_RS09810 (DAPPPG734_09975) 2122282..2122617 - 336 WP_031592301.1 gamma-glutamylcyclotransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(4-102)

Antitoxin

Cro/C1-type helix-turn-helix domain

(9-54)


Sequences

Toxin        


Download         Length: 438 a.a.        Molecular weight: 49103.72 Da        Isoelectric Point: 8.8383

>T296232 WP_031592298.1 NZ_OW970315:2116395-2117708 [Pantoea agglomerans]
MQRLIAWMNGERVGVLTRQRNGAHEFQYDTAWLSNPLSRPLSLSMPLQVKAITSHAVINFFDNLLPDSPLIRDRIVARYQ
IKSRQPFDLLQEVGRDSVGATMLLPPDMPLPALQARYEVLDETRLESVLSAYQSDIPLGMLREETDFRISVAGAQEKTAL
LLTDEGWSIPAGATPTSHIIKLPIGEIKQPAATLDMRESVENEYLCLALARALGIDVPQATIIRAGQMRALAVERFDRRW
SRDKTRLIRLPQEDFCQALGLPSSTKYESDGGPGIAEIMQILMGSSNAIEDRYRFMMFQVFQWLIGATDGHAKNFSLFIE
RGGSYRLTPFYDVISAYPVLGGTGLNKRALKLAMGLRATKGKKTEIDKIFPRHFIATAKSVSFDRDSLQQIFDFFIKAFP
QAVVSVRDALPPGFPQHIADAIFSHSLIMLERLRHKE

Download         Length: 1314 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9363.61 Da        Isoelectric Point: 5.0775

>AT296232 WP_022625644.1 NZ_OW970315:2116147-2116395 [Pantoea agglomerans]
MIYSPLQLANRLKLIRQRNGWTQSELAKKVGLKQATISHFENAPDSTSLATLFKLLQSLELSLEVQEKEEASAPQLHDED
EW

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References