Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1948321..1948465 Replicon chromosome
Accession NZ_OW969912
Organism Klebsiella variicola isolate 0

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1948357..1948459 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1948321..1948465 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ196_RS09380 (AN2340V1_1793) 1943451..1945511 + 2061 WP_230138528.1 oligopeptidase B -
LQ196_RS09385 (AN2340V1_1794) 1945515..1946174 - 660 WP_012541259.1 exodeoxyribonuclease X -
LQ196_RS09390 (AN2340V1_1795) 1946253..1946483 - 231 WP_012541260.1 DNA polymerase III subunit theta -
LQ196_RS09395 (AN2340V1_1796) 1946597..1946971 + 375 WP_012541261.1 CopC domain-containing protein YobA -
LQ196_RS09400 (AN2340V1_1797) 1946975..1947844 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
LQ196_RS09405 (AN2340V1_1798) 1947861..1948199 + 339 WP_008804271.1 YebY family protein -
- 1948321..1948465 - 145 - - Antitoxin
- 1948357..1948459 + 103 - - Toxin
LQ196_RS09410 (AN2340V1_1799) 1948844..1948987 - 144 WP_046621074.1 Ecr family regulatory small membrane protein -
LQ196_RS09415 (AN2340V1_1800) 1949091..1950059 - 969 WP_162493241.1 VirK/YbjX family protein -
LQ196_RS09420 (AN2340V1_1801) 1950216..1950869 + 654 WP_008804273.1 protein-serine/threonine phosphatase -
LQ196_RS09425 (AN2340V1_1802) 1950866..1951057 - 192 WP_002911395.1 YebW family protein -
LQ196_RS09430 (AN2340V1_1803) 1951155..1951394 - 240 WP_002911393.1 YebV family protein -
LQ196_RS09435 (AN2340V1_1804) 1951510..1952943 - 1434 WP_230138529.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T296219 NZ_OW969912:1948357-1948459 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT296219 NZ_OW969912:c1948465-1948321 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References