Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 787363..788052 Replicon chromosome
Accession NZ_OW969912
Organism Klebsiella variicola isolate 0

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag LQ196_RS03890 Protein ID WP_230138433.1
Coordinates 787714..788052 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag LQ196_RS03885 Protein ID WP_230138432.1
Coordinates 787363..787689 (+) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ196_RS03860 (AN2340V1_0740) 783251..783718 - 468 WP_230138429.1 zinc-ribbon domain-containing protein -
LQ196_RS03865 (AN2340V1_0741) 783984..784199 - 216 WP_154924526.1 AlpA family phage regulatory protein -
LQ196_RS03870 (AN2340V1_0742) 784309..784956 - 648 WP_230138430.1 inovirus Gp2 family protein -
LQ196_RS03875 (AN2340V1_0743) 785675..786643 + 969 WP_230138431.1 hypothetical protein -
LQ196_RS03880 (AN2340V1_0744) 786847..787320 + 474 WP_049130829.1 DNA repair protein RadC -
LQ196_RS03885 (AN2340V1_0745) 787363..787689 + 327 WP_230138432.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
LQ196_RS03890 (AN2340V1_0746) 787714..788052 + 339 WP_230138433.1 TA system toxin CbtA family protein Toxin
LQ196_RS03895 (AN2340V1_0747) 788166..788993 + 828 WP_230138434.1 DUF4942 domain-containing protein -
LQ196_RS03900 (AN2340V1_0748) 789335..790723 - 1389 WP_060619870.1 MFS transporter -
LQ196_RS03905 (AN2340V1_0749) 790853..791782 + 930 WP_029602171.1 LysR family transcriptional regulator -
LQ196_RS03910 (AN2340V1_0750) 792140..792943 - 804 WP_032731230.1 carboxymuconolactone decarboxylase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-107)

Antitoxin

Antitoxin CbeA

(7-107)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12793.76 Da        Isoelectric Point: 8.5135

>T296216 WP_230138433.1 NZ_OW969912:787714-788052 [Klebsiella variicola]
MKTLPANQRVAKPCPPPVLVWQTLLTRLLEQHYGLTLNDTPFSDENVIQEHINAGITLADAVNFLVEKYELVRIDRRGFN
CQEQSPYLRAVDILRARQATGLLRQSQLPSIR

Download         Length: 339 bp

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12471.23 Da        Isoelectric Point: 6.5937

>AT296216 WP_230138432.1 NZ_OW969912:787363-787689 [Klebsiella variicola]
MEKHVNPEWGLRCVVMPRFGARLVQEGNRLHYLADRAGITGTFNEEQCHQLNSAFPHFIEQMELMLLSGELNPRHAHRVT
LYHNELTCEADTLGSCGYVYIVIYPTQR

Download         Length: 327 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References