296207

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 4758115..4758781 Replicon chromosome
Accession NZ_OW969904
Organism Citrobacter freundii isolate 0

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag LQ142_RS23325 Protein ID WP_134214823.1
Coordinates 4758422..4758781 (-) Length 120 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag LQ142_RS23320 Protein ID WP_134214821.1
Coordinates 4758115..4758432 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ142_RS23280 (4753403) 4753403..4754227 + 825 WP_048216971.1 PTS system mannose/fructose/sorbose family transporter subunit IID -
LQ142_RS23285 (4754295) 4754295..4755518 + 1224 WP_003031639.1 L-sorbose 1-phosphate reductase -
LQ142_RS23290 (4755520) 4755520..4756332 + 813 WP_134214817.1 shikimate 5-dehydrogenase -
LQ142_RS23295 (4756366) 4756366..4756683 - 318 WP_054527950.1 CcdB family protein -
LQ142_RS23300 (4756683) 4756683..4756976 - 294 WP_003844689.1 type II toxin-antitoxin system CcdA family antitoxin -
LQ142_RS23305 (4757073) 4757073..4757438 - 366 WP_134214819.1 hypothetical protein -
LQ142_RS23310 (4757570) 4757570..4757743 + 174 WP_032938222.1 hypothetical protein -
LQ142_RS23315 (4757814) 4757814..4757975 + 162 WP_003841416.1 phage protein -
LQ142_RS23320 (4758115) 4758115..4758432 - 318 WP_134214821.1 helix-turn-helix transcriptional regulator Antitoxin
LQ142_RS23325 (4758422) 4758422..4758781 - 360 WP_134214823.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LQ142_RS23330 (4758995) 4758995..4759684 + 690 WP_003841421.1 dipeptidase PepE -
LQ142_RS23335 (4759831) 4759831..4761462 - 1632 WP_003031618.1 Na/Pi cotransporter family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-106)

Antitoxin

Cro/C1-type helix-turn-helix domain

(34-87)


Sequences

Toxin        


Download         Length: 120 a.a.        Molecular weight: 13456.53 Da        Isoelectric Point: 10.2555

>T296207 WP_134214823.1 NZ_OW969904:c4758781-4758422 [Citrobacter freundii]
MTKPLYWVGQARKDLLAMPEHVRDTFGFAFWLAQQGKQHSQTKPLKGFGGAGVLEVVEDYHGSAWRAVYTIQLKNAVYVL
HVFQKKSVSGKATPKPEIDLIYQRLKAAQRHAQESGYVI

Download         Length: 360 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11504.44 Da        Isoelectric Point: 8.9375

>AT296207 WP_134214821.1 NZ_OW969904:c4758432-4758115 [Citrobacter freundii]
MSYEVEASSGNVYVDLGAYDAEQMQLKAQLAMVIGEILQRKGLTQQQAAQLLGMTQPKLSNLLRGQFRGISEAKMLECLV
RLGRDVEIVVGKEGNMSGKLKVKFG

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References