Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeV-yafW/CbtA-CbeA
Location 684361..685084 Replicon chromosome
Accession NZ_OW969904
Organism Citrobacter freundii isolate 0

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag LQ142_RS03305 Protein ID WP_181506521.1
Coordinates 684764..685084 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name yafW Uniprot ID -
Locus tag LQ142_RS03300 Protein ID WP_230126870.1
Coordinates 684361..684696 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ142_RS03280 (679386) 679386..680399 + 1014 WP_109846053.1 SIR2 family protein -
LQ142_RS03285 (680409) 680409..682142 + 1734 WP_085119320.1 ATP-binding protein -
LQ142_RS03290 (682475) 682475..683374 - 900 WP_230126868.1 SMEK domain-containing protein -
LQ142_RS03295 (683867) 683867..684346 + 480 WP_063941847.1 DNA repair protein RadC -
LQ142_RS03300 (684361) 684361..684696 + 336 WP_230126870.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
LQ142_RS03305 (684764) 684764..685084 + 321 WP_181506521.1 TA system toxin CbtA family protein Toxin
LQ142_RS03310 (685198) 685198..686031 + 834 WP_230126872.1 DUF4942 domain-containing protein -
LQ142_RS03320 (686335) 686335..686841 + 507 WP_016151005.1 G/U mismatch-specific DNA glycosylase -
LQ142_RS03325 (686872) 686872..688869 - 1998 WP_016151004.1 TonB-dependent receptor -
LQ142_RS03330 (688880) 688880..689929 - 1050 WP_003846277.1 YncE family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 644961..686031 41070


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(5-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12150.85 Da        Isoelectric Point: 6.4795

>T296195 WP_181506521.1 NZ_OW969904:684764-685084 [Citrobacter freundii]
MQISTVPATLPVSSRLSPVQVWQQLLTYLLEHHYGLTLNDTPFHNESAIREHIEAGITLADALNFLVERYELIRTDRKGF
TWQEQTPFLTATDILRARRATGLMNT

Download         Length: 321 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12563.27 Da        Isoelectric Point: 6.4771

>AT296195 WP_230126870.1 NZ_OW969904:684361-684696 [Citrobacter freundii]
MNKEVTQTWGLKRDITLCFGARLVQEGHRLHFLADRAGFNGSFSEMQARDLDEAFPHFVTHMELMLLSGELNPRCGHCVT
LYRNGLTCEADTLGSHGYVYIAIYPSNQVKD

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References