Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX(toxin)
Location 4499624..4500443 Replicon chromosome
Accession NZ_OW969781
Organism Klebsiella oxytoca isolate 328

Toxin (Protein)


Gene name yjhX Uniprot ID J5WT09
Locus tag LQ195_RS21100 Protein ID WP_004110819.1
Coordinates 4500186..4500443 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag LQ195_RS21095 Protein ID WP_210669405.1
Coordinates 4499624..4500175 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ195_RS21070 (AN2363V1_4133) 4494694..4495242 - 549 WP_004099233.1 type 1 fimbrial major subunit FimA -
LQ195_RS21075 (AN2363V1_4134) 4495615..4496382 + 768 WP_004099232.1 winged helix-turn-helix domain-containing protein -
LQ195_RS21080 (AN2363V1_4135) 4497010..4497687 + 678 WP_135800006.1 sigma-70 region 4 domain-containing protein -
LQ195_RS21085 4497978..4498742 - 765 WP_224227635.1 class I SAM-dependent methyltransferase -
LQ195_RS21090 4499118..4499510 - 393 Protein_4150 class I SAM-dependent methyltransferase -
LQ195_RS21095 (AN2363V1_4137) 4499624..4500175 - 552 WP_210669405.1 N-acetyltransferase Antitoxin
LQ195_RS21100 (AN2363V1_4138) 4500186..4500443 - 258 WP_004110819.1 YjhX family toxin Toxin
LQ195_RS21105 (AN2363V1_4139) 4501024..4502208 + 1185 WP_004099225.1 mannonate dehydratase -
LQ195_RS21110 (AN2363V1_4140) 4502283..4503758 + 1476 WP_047720344.1 fructuronate reductase -
LQ195_RS21115 (AN2363V1_4141) 4503894..4504670 + 777 WP_004099223.1 Uxu operon transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(17-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9552.07 Da        Isoelectric Point: 11.1381

>T296191 WP_004110819.1 NZ_OW969781:c4500443-4500186 [Klebsiella oxytoca]
MNLSRQEQRTLHVLAKGGRIAHIRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20158.97 Da        Isoelectric Point: 6.8799

>AT296191 WP_210669405.1 NZ_OW969781:c4500175-4499624 [Klebsiella oxytoca]
MTNHNFTFHITSERDADDIREVETRAFGFSKEADLVAALLNDESAHSSLSLLAKHNGKAVGHILFTLATFKGESDSPMMH
ILAPLAVVPEYQGVGVGGLLIQRGIEHLKAAGSEAVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMLQRLSS
RPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H3H6Y2

Antitoxin

Source ID Structure

References