296179

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 3955166..3955857 Replicon chromosome
Accession NZ_OW969711
Organism Citrobacter koseri isolate 0

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag LQV24_RS18850 Protein ID WP_205612697.1
Coordinates 3955166..3955519 (-) Length 118 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag LQV24_RS18855 Protein ID WP_032686426.1
Coordinates 3955540..3955857 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQV24_RS18840 (3951527) 3951527..3952897 - 1371 WP_049010418.1 tyrosine phenol-lyase -
LQV24_RS18845 (3953922) 3953922..3954929 - 1008 WP_230012183.1 restriction endonuclease -
LQV24_RS18850 (3955166) 3955166..3955519 - 354 WP_205612697.1 TA system toxin CbtA family protein Toxin
LQV24_RS18855 (3955540) 3955540..3955857 - 318 WP_032686426.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
LQV24_RS18860 (3955876) 3955876..3956097 - 222 WP_071602634.1 DUF987 domain-containing protein -
LQV24_RS18865 (3956106) 3956106..3956582 - 477 WP_032686427.1 RadC family protein -
LQV24_RS18870 (3956598) 3956598..3957056 - 459 WP_230012187.1 antirestriction protein -
LQV24_RS18875 (3957142) 3957142..3957378 - 237 Protein_3699 DUF905 domain-containing protein -
LQV24_RS18880 (3957456) 3957456..3957866 - 411 WP_230012190.1 hypothetical protein -
LQV24_RS18885 (3957933) 3957933..3958370 - 438 WP_230012193.1 hypothetical protein -
LQV24_RS18890 (3958412) 3958412..3958948 - 537 WP_230012195.1 DUF4339 domain-containing protein -
LQV24_RS18895 (3958974) 3958974..3959681 - 708 WP_057067447.1 DeoR family transcriptional regulator -
LQV24_RS18900 (3959890) 3959890..3960714 - 825 WP_008783817.1 DUF932 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3955166..3986628 31462


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-109)

Antitoxin

Antitoxin CbeA

(5-104)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13285.26 Da        Isoelectric Point: 7.2783

>T296179 WP_205612697.1 NZ_OW969711:c3955519-3955166 [Citrobacter koseri]
MKTLPATTPQAATLCLSPVAVWQMLLARLLEQHYGLTLNDTPFSDETVIQEHIDAGISLADAVNFLVEKFGLVRIDRRGF
NWQEQSPYLRAVDILRARQATGLLKRNRISAAREHWE

Download         Length: 354 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11789.39 Da        Isoelectric Point: 6.3088

>AT296179 WP_032686426.1 NZ_OW969711:c3955857-3955540 [Citrobacter koseri]
MSNITWGLQCDITPRLGTRLVQEGNQLHYLADRASITGKFSDTECLKLDVAFPHFISQMESMLTTGEMNPRHAHCVTLYH
NGFTCEADTLGSCGYVYIAVYPTQR

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References