Detailed information of TA system TA029616

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 1314862..1315390
• Replicon: chromosome
• Accession: NC_021661
• Organism: Psychrobacter sp. G

Toxin (Protein)

• Gene name: relE
• Uniprot ID: T1EBG3
• Locus tag: PSYCG_RS05575
• Protein ID: WP_020443321.1
• Coordinates: 1314862..1315149 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: X0RAH8
• Locus tag: PSYCG_RS05580
• Protein ID: WP_020443322.1
• Coordinates: 1315139..1315390 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PSYCG_RS05550	1310183..1311001	-	819	WP_020443317.1	Nif3-like dinuclear metal center hexameric protein	-
PSYCG_RS05555	1311261..1312589	+	1329	WP_020443318.1	trypsin-like peptidase domain-containing protein	-
PSYCG_RS05560	1312714..1312980	-	267	WP_011513453.1	2Fe-2S iron-sulfur cluster binding domain-containing protein	-
PSYCG_RS05565	1313178..1314311	-	1134	WP_020443319.1	ribonucleotide-diphosphate reductase subunit beta	-
PSYCG_RS05570	1314384..1314767	-	384	WP_020443320.1	hypothetical protein	-
PSYCG_RS05575	1314862..1315149	-	288	WP_020443321.1	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	Toxin
PSYCG_RS05580	1315139..1315390	-	252	WP_020443322.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
PSYCG_RS13115	1315665..1316444	-	780	WP_020443323.1	toll/interleukin-1 receptor domain-containing protein	-
PSYCG_RS05590	1316481..1316957	-	477	WP_020443324.1	TIR domain-containing protein	-
PSYCG_RS05595	1316954..1318348	-	1395	WP_020443325.1	SIR2 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (8-72)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11041.89 Da
• Isoelectric Point: 10.5715

>T29616 WP_020443321.1 NC_021661:c1315149-1314862 [Psychrobacter sp. G]
MTYSLEFHPLALKEWKKIAPSIQQQFKKKLQQRLSNPHVPASKLTGHTDTYKIKLRTVGYRLVYTVKDDVVVVYVLAVGK
RENNKVYDNLATRQP

Nucleotide

• Length: 288 bp

>T29616 NC_021661:c1315149-1314862 [Psychrobacter sp. G]
ATGACTTATAGCCTTGAGTTTCACCCGTTAGCGTTAAAAGAATGGAAAAAGATAGCGCCAAGTATCCAGCAGCAGTTTAA
GAAAAAATTACAGCAGCGATTGTCAAACCCTCATGTGCCTGCGTCAAAACTCACAGGACATACCGATACTTATAAAATCA
AATTACGCACCGTAGGGTATCGTCTGGTATATACCGTAAAAGACGACGTGGTGGTGGTTTATGTATTGGCAGTTGGCAAA
AGAGAAAACAACAAAGTGTATGACAATCTAGCGACGCGTCAGCCATGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9050.36 Da
• Isoelectric Point: 4.2493

>AT29616 WP_020443322.1 NC_021661:c1315390-1315139 [Psychrobacter sp. G]
MQPIFATQTASISELKANPSALIKQSDGESIAILNHNKPVAYLVSTDVFERMMEAMDDMALSQTVSARLNDGQIPIKVTL
DDL

Nucleotide

• Length: 252 bp

>AT29616 NC_021661:c1315390-1315139 [Psychrobacter sp. G]
ATGCAACCAATATTTGCCACACAGACAGCCAGTATCTCAGAATTAAAGGCCAACCCATCGGCACTGATTAAACAGTCAGA
TGGTGAGTCCATTGCTATCTTAAACCACAACAAACCCGTGGCTTACTTAGTCTCAACAGACGTCTTTGAGCGCATGATGG
AAGCGATGGACGATATGGCACTCAGCCAAACCGTTAGCGCACGATTAAATGATGGGCAGATACCGATAAAGGTAACGTTG
GATGACTTATAG

Structures

Toxin

• AlphaFold DB: T1EBG3

Antitoxin

• AlphaFold DB: X0RAH8