Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX(toxin)
Location 4593731..4594550 Replicon chromosome
Accession NZ_OW969659
Organism Klebsiella oxytoca isolate 36

Toxin (Protein)


Gene name yjhX Uniprot ID J5WT09
Locus tag LQ206_RS21575 Protein ID WP_004110819.1
Coordinates 4594293..4594550 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag LQ206_RS21570 Protein ID WP_016809596.1
Coordinates 4593731..4594282 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ206_RS21535 (AI2918V1_4230) 4588735..4589778 + 1044 WP_016809310.1 alpha/beta hydrolase -
LQ206_RS21540 (AI2918V1_4231) 4589846..4590274 + 429 WP_016809309.1 cyclophilin-like fold protein -
LQ206_RS21545 (AI2918V1_4232) 4590467..4591000 - 534 Protein_4244 MFS transporter -
LQ206_RS21550 4591503..4591706 - 204 Protein_4245 VOC family protein -
LQ206_RS21555 (AI2918V1_4233) 4591706..4591915 - 210 WP_196089984.1 hypothetical protein -
LQ206_RS21560 4592085..4592849 - 765 WP_224226441.1 class I SAM-dependent methyltransferase -
LQ206_RS21565 4593243..4593617 - 375 Protein_4248 class I SAM-dependent methyltransferase -
LQ206_RS21570 (AI2918V1_4235) 4593731..4594282 - 552 WP_016809596.1 N-acetyltransferase Antitoxin
LQ206_RS21575 (AI2918V1_4236) 4594293..4594550 - 258 WP_004110819.1 YjhX family toxin Toxin
LQ206_RS21580 (AI2918V1_4237) 4595132..4596316 + 1185 WP_016809597.1 mannonate dehydratase -
LQ206_RS21585 (AI2918V1_4238) 4596391..4597866 + 1476 WP_004110817.1 fructuronate reductase -
LQ206_RS21590 (AI2918V1_4239) 4598002..4598778 + 777 WP_004099223.1 Uxu operon transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(17-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9552.07 Da        Isoelectric Point: 11.1381

>T296155 WP_004110819.1 NZ_OW969659:c4594550-4594293 [Klebsiella oxytoca]
MNLSRQEQRTLHVLAKGGRIAHIRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20169.01 Da        Isoelectric Point: 6.8799

>AT296155 WP_016809596.1 NZ_OW969659:c4594282-4593731 [Klebsiella oxytoca]
MTNHNFTFHITSERDADDIREVETRAFGFSKEADLVAALLNDESAHPSLSLLAKHNGKAVGHILFTLATFKGESDSPMMH
ILAPLAVVPEYQGVGVGGLLIQRGIEHLKAAGSEAVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMLQRLSS
RPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H3H6Y2

Antitoxin

Source ID Structure

References