Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 854662..855319 Replicon chromosome
Accession NZ_OW969633
Organism Klebsiella aerogenes isolate 57

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag LQ131_RS04115 Protein ID WP_020077981.1
Coordinates 854909..855319 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A0H3FJK6
Locus tag LQ131_RS04110 Protein ID WP_015369791.1
Coordinates 854662..854928 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ131_RS04085 (849889) 849889..851322 - 1434 WP_230132708.1 6-phospho-beta-glucosidase BglA -
LQ131_RS04090 (851442) 851442..852170 - 729 WP_020077980.1 MurR/RpiR family transcriptional regulator -
LQ131_RS04095 (852221) 852221..852532 + 312 WP_015703422.1 N(4)-acetylcytidine aminohydrolase -
LQ131_RS04100 (852697) 852697..853356 + 660 WP_008806429.1 hemolysin III family protein -
LQ131_RS04105 (853455) 853455..854438 - 984 WP_015369790.1 tRNA-modifying protein YgfZ -
LQ131_RS04110 (854662) 854662..854928 + 267 WP_015369791.1 FAD assembly factor SdhE Antitoxin
LQ131_RS04115 (854909) 854909..855319 + 411 WP_020077981.1 protein YgfX Toxin
LQ131_RS04120 (855327) 855327..855848 - 522 WP_015369793.1 flavodoxin FldB -
LQ131_RS04125 (855949) 855949..856845 + 897 WP_015703420.1 site-specific tyrosine recombinase XerD -
LQ131_RS04130 (856868) 856868..857581 + 714 WP_015369795.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
LQ131_RS04135 (857587) 857587..859320 + 1734 WP_032715785.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15873.66 Da        Isoelectric Point: 10.0200

>T296140 WP_020077981.1 NZ_OW969633:854909-855319 [Klebsiella aerogenes]
VVLWQSDLRISWRSQWFSLLLHGVVAAIVLLMPWPLSYTPIWLLLLSLVVFDCVRSQRRIHACQGEIKLLIDSRLRWQKT
EWDIVGTPWVISSGMLLRLKHAESGRSQHLWVAADSMDAGEWRDLRRLVLQKPAHD

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10579.09 Da        Isoelectric Point: 5.6963

>AT296140 WP_015369791.1 NZ_OW969633:854662-854928 [Klebsiella aerogenes]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDTLSDDDKRLFIRLLENDDPDLFNWLMNHGKPADAQLQRMINLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0H3FJK6

References