Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 788138..788795 Replicon chromosome
Accession NZ_OW968431
Organism Klebsiella quasipneumoniae isolate 0

Toxin (Protein)


Gene name cptA Uniprot ID A0A2A5MNX1
Locus tag LQ152_RS03875 Protein ID WP_004205323.1
Coordinates 788385..788795 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID W8UQ37
Locus tag LQ152_RS03870 Protein ID WP_002916312.1
Coordinates 788138..788404 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ152_RS03845 (783347) 783347..784780 - 1434 WP_004205314.1 6-phospho-beta-glucosidase BglA -
LQ152_RS03850 (784899) 784899..785627 - 729 WP_004205316.1 MurR/RpiR family transcriptional regulator -
LQ152_RS03855 (785677) 785677..785988 + 312 WP_004205318.1 N(4)-acetylcytidine aminohydrolase -
LQ152_RS03860 (786151) 786151..786810 + 660 WP_004205319.1 hemolysin III family protein -
LQ152_RS03865 (786909) 786909..787892 - 984 WP_182971700.1 tRNA-modifying protein YgfZ -
LQ152_RS03870 (788138) 788138..788404 + 267 WP_002916312.1 FAD assembly factor SdhE Antitoxin
LQ152_RS03875 (788385) 788385..788795 + 411 WP_004205323.1 protein YgfX Toxin
LQ152_RS03880 (788802) 788802..789323 - 522 WP_048325670.1 flavodoxin FldB -
LQ152_RS03885 (789424) 789424..790320 + 897 WP_004144729.1 site-specific tyrosine recombinase XerD -
LQ152_RS03890 (790343) 790343..791056 + 714 WP_002916301.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
LQ152_RS03895 (791062) 791062..792795 + 1734 WP_004205327.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16035.83 Da        Isoelectric Point: 11.4778

>T296130 WP_004205323.1 NZ_OW968431:788385-788795 [Klebsiella quasipneumoniae]
VVLWQSDLRISWRAQWFSLLLHGVVAALVLLVPWPLSYTPIWLLLLSLVVFDCVRSQRRIHARRGEIKLLTDSRLRWQNA
DWEILGTPWVINSGMLLRLRHVDTRRGQHLWLAADSMDAGEWRDLRRLVLQKPAQE

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10480.98 Da        Isoelectric Point: 5.1116

>AT296130 WP_002916312.1 NZ_OW968431:788138-788404 [Klebsiella quasipneumoniae]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDTLSDADKQLFIRLLENDDPDLFNWLMNHGKPADAELQRMVTLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2A5MNX1

Antitoxin

Source ID Structure
AlphaFold DB A0A0H3GY41

References