296115

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 939755..940470 Replicon chromosome
Accession NZ_OW968417
Organism Enterobacter cloacae isolate 764

Toxin (Protein)


Gene name ypjF Uniprot ID A0A8I0UM05
Locus tag LQ125_RS04530 Protein ID WP_023303149.1
Coordinates 940102..940470 (+) Length 123 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID A0A8I0UJV2
Locus tag LQ125_RS04525 Protein ID WP_023303148.1
Coordinates 939755..940081 (+) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ125_RS04500 (AI3013V2_0868) 934789..936054 + 1266 WP_045324920.1 hypothetical protein -
LQ125_RS04505 (AI3013V2_0869) 936363..936797 + 435 WP_023303144.1 hypothetical protein -
LQ125_RS04510 (AI3013V2_0870) 936856..937695 + 840 WP_023303145.1 hypothetical protein -
LQ125_RS04515 (AI3013V2_0872) 938385..939206 + 822 WP_023303146.1 DUF932 domain-containing protein -
LQ125_RS04520 (AI3013V2_0873) 939272..939742 + 471 WP_023303147.1 DNA repair protein RadC -
LQ125_RS04525 (AI3013V2_0874) 939755..940081 + 327 WP_023303148.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
LQ125_RS04530 (AI3013V2_0875) 940102..940470 + 369 WP_023303149.1 TA system toxin CbtA family protein Toxin
LQ125_RS04535 (AI3013V2_0876) 941250..942164 - 915 WP_045308930.1 hypothetical protein -
LQ125_RS04540 (AI3013V2_0877) 942726..943019 - 294 WP_163347504.1 hypothetical protein -
LQ125_RS04545 (AI3013V2_0879) 943916..944116 + 201 WP_045308928.1 hypothetical protein -
LQ125_RS04550 (AI3013V2_0880) 944140..944748 - 609 WP_131631787.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 918837..950872 32035


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-111)

Antitoxin

Antitoxin CbeA

(7-107)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13727.91 Da        Isoelectric Point: 8.2822

>T296115 WP_023303149.1 NZ_OW968417:940102-940470 [Enterobacter cloacae]
MKNLPATISRAAKPCLSPVAVWQMLLTRLLEQHYGLTLNDTPFSDETVIKEHIDAGIILADAVNFLVDKYELVRIDRRGF
SSQGQVPYLTVTDILHARRACGLMKSCSYREVSNIVLSHSRQ

Download         Length: 369 bp

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12215.04 Da        Isoelectric Point: 7.0266

>AT296115 WP_023303148.1 NZ_OW968417:939755-940081 [Enterobacter cloacae]
MSLIPAHEWGIKSDIVPRLGVRLVQEGNRLHYLADRASITGKFSDAECLKLDIVFPHFIRQMESMLTTGEMNSRHAHCVT
LYHNGFTCEADTLGSCGYVYIAIYPTQR

Download         Length: 327 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References