Detailed information of TA system TA296101

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/LOTUS_5_Limkain_b1(toxin)
• Location: 4814416..4815032
• Replicon: chromosome
• Accession: NZ_OW968328
• Organism: Enterobacter cloacae isolate 1382

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: LQ108_RS22865
• Protein ID: WP_230137126.1
• Coordinates: 4814416..4814787 (-)
• Length: 124 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: LQ108_RS22870
• Protein ID: WP_046889539.1
• Coordinates: 4814790..4815032 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (6-115)

Antitoxin

• Ribbon-helix-helix protein, CopG (12-49)

Sequences

Toxin

Protein

• Length: 124 a.a.
• Molecular weight: 13627.72 Da
• Isoelectric Point: 6.6407

>T296101 WP_230137126.1 NZ_OW968328:c4814787-4814416 [Enterobacter cloacae]
MNNMAVFDTNILIDLFNNRVEAADAIDHAASHRAISLITWMEVMVGARRHGHEAKTAAVMGAFEVIDVSRDIAERSVLLR
EKHGMKLPDAIILATAQSRKCPLISRNTKDFAGIDEVVTPYQL

Nucleotide

• Length: 372 bp

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 9413.69 Da
• Isoelectric Point: 4.3224

>AT296101 WP_046889539.1 NZ_OW968328:c4815032-4814790 [Enterobacter cloacae]
MSVLAELDMGRILIDLSDDVIQRLDNLKQLRNQPRAELLREAIELYLDQQSSSVIRDALGLWGDKKEDGLEYERKLREEW

Nucleotide

• Length: 243 bp